Isolation and structure of pinnatoxin D, a new shellfish poison from the Okinawan bivalve Pinna muricata

被引：118

作者：

Chou, T

Haino, T

Kuramoto, M

Uemura, D

机构：

[1] SHIZUOKA UNIV, FAC SCI, DEPT CHEM, OHYA, SHIZUOKA 422, JAPAN

[2] SAGAMI CHEM RES CTR, SAGAMIHARA, KANAGAWA 229, JAPAN

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 23期

关键词：

D O I：

10.1016/0040-4039(96)00753-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new shellfish poison, pinnatoxin D, has been isolated from the Okinawan bivalve Pinna muricata. The planar structure was elucidated by extensive 2D NMR experiments, and the relative stereochemistry was deduced by NOESY data and (3)J(H-H) coupling constants. Pinnatoxin D is a novel amphoteric carbocyclic compound which is composed of a 6,7-spiro ring, a 5,6-bicyclo ring and a 6,5,6-trispiro ketal involving 15 chiral centers. (C) 1996 Elsevier Science Ltd.

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页码：4027 / 4030

页数：4

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