Psychiatrists' Attitudes toward Metabolic Adverse Events in Patients with Schizophrenia

被引:9
作者
Sugawara, Norio [1 ,2 ]
Yasui-Furukori, Norio [1 ,2 ]
Yamazaki, Manabu [3 ]
Shimoda, Kazutaka [2 ,4 ]
Mori, Takao [3 ]
Sugai, Takuro [2 ,5 ]
Suzuki, Yutaro [2 ,5 ]
Someya, Toshiyuki [2 ,5 ]
机构
[1] Hirosaki Univ, Sch Med, Dept Neuropsychiat, Hirosaki, Aomori 036, Japan
[2] Japanese Soc Clin Neuropsychopharmacol, Tokyo, Japan
[3] Japan Psychiat Hosp Assoc, Tokyo, Japan
[4] Dokkyo Med Univ, Sch Med, Dept Psychiat, Mibu, Tochigi, Japan
[5] Niigata Univ, Grad Sch Med & Dent Sci, Dept Psychiat, Niigata, Japan
关键词
ANTIPSYCHOTIC MEDICATIONS; CARDIOVASCULAR-DISEASE; DIABETES-MELLITUS; WEIGHT-GAIN; GLUCOSE; PHARMACOTHERAPY; RISPERIDONE; PREVALENCE; OLANZAPINE; INPATIENTS;
D O I
10.1371/journal.pone.0086826
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background: There is growing concern about the metabolic abnormalities in patients with schizophrenia. Aims: The aim of this study was to assess the attitudes of psychiatrists toward metabolic adverse events in patients with schizophrenia. Method: A brief questionnaire was constructed to cover the following broad areas: the psychiatrists' recognition of the metabolic risk of antipsychotic therapy, pattern of monitoring patients for physical risks, practice pattern for physical risks, and knowledge of metabolic disturbance. In March 2012, the questionnaire was mailed to 8,482 psychiatrists who were working at hospitals belonging to the Japan Psychiatric Hospitals Association. Results: The overall response rate was 2,583/8,482 (30.5%). Of the respondents, 85.2% (2,200/2,581) reported that they were concerned about prescribing antipsychotics that have a risk of elevating blood sugar; 47.6% (1,201/2,524) stated that their frequency of monitoring patients under antipsychotic treatment was based on their own experiences; and only 20.6% (5,22/2,534) of respondents answered that the frequency with which they monitored their patients was sufficient to reduce the metabolic risks. Conclusions: Psychiatrists practicing in Japan were generally aware and concerned about the metabolic risks for patients being treated with antipsychotics. Although psychiatrists should monitor their patients for metabolic abnormalities to balance these risks, a limited number of psychiatrists answered that the frequency with which they monitored patients to reduce the metabolic risks was sufficient. Promotion of the best practices of pharmacotherapy and monitoring is needed for psychiatrists treating patients with schizophrenia.
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页数:5
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