A near-infrared fluorescent probe for hydrogen sulfide in living cells

被引：57

作者：

Zheng, Yi ^{[1
,2
]}

Zhao, Miao ^{[1
]}

Qiao, Qinglong ^{[1
]}

Liu, Huiying ^{[1
]}

Lang, Haijing ^{[1
]}

Xu, Zhaochao ^{[1
]}

机构：

[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

[2] Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang 110016, Peoples R China

来源：

DYES AND PIGMENTS | 2013年 / 98卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Fluorescent probes; Near-infrared; Hydrogen sulfide; Azide; Living cells imaging; High selectivity; CHEMOSENSOR; H2S;

D O I：

10.1016/j.dyepig.2013.03.014

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Fluorescent probes for hydrogen sulfide have received considerable attention because of the biological significance of H2S recognized recently. However, near-infrared fluorescent probes for H2S are still rare. In this work, a new near-infrared fluorescent probe for H2S was developed based on the reduction reaction of azide with H2S to amine based on the fluorophore of dicyanomethylene-4H-chromene because of its long excitation and emission wavelength. The probe has a high selectivity for H2S over competitive anions and sulfide-containing analytes. Finally, the probe was applied to sense H2S in living cells. Crown Copyright (c) 2013 Published by Elsevier Ltd. All rights reserved.

引用

页码：367 / 371

页数：5

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