A near-infrared fluorescent probe for hydrogen sulfide in living cells

被引：57
|
作者：
Zheng, Yi [1 ,2 ]
Zhao, Miao [1 ]
Qiao, Qinglong [1 ]
Liu, Huiying [1 ]
Lang, Haijing [1 ]
Xu, Zhaochao [1 ]
机构：
[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
[2] Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang 110016, Peoples R China
来源：
DYES AND PIGMENTS | 2013年 / 98卷 / 03期
基金：
中国国家自然科学基金;
关键词：
Fluorescent probes; Near-infrared; Hydrogen sulfide; Azide; Living cells imaging; High selectivity; CHEMOSENSOR; H2S;
D O I：
10.1016/j.dyepig.2013.03.014
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Fluorescent probes for hydrogen sulfide have received considerable attention because of the biological significance of H2S recognized recently. However, near-infrared fluorescent probes for H2S are still rare. In this work, a new near-infrared fluorescent probe for H2S was developed based on the reduction reaction of azide with H2S to amine based on the fluorophore of dicyanomethylene-4H-chromene because of its long excitation and emission wavelength. The probe has a high selectivity for H2S over competitive anions and sulfide-containing analytes. Finally, the probe was applied to sense H2S in living cells. Crown Copyright (c) 2013 Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：367 / 371
页数：5
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