Recommendation of the 5th Canadian Consensus Conference on the diagnosis and treatment of dementia

被引：170

作者：

Ismail, Zahinoor ^{[1
]}

Black, Sandra E. ^{[2
]}

Camicioli, Richard ^{[3
]}

Chertkow, Howard ^{[4
]}

Herrmann, Nathan ^{[5
]}

Laforce, Robert, Jr. ^{[6
,7
]}

Montero-Odasso, Manuel ^{[8
,9
,10
,11
]}

Rockwood, Kenneth ^{[12
]}

Rosa-Neto, Pedro ^{[13
]}

Seitz, Dallas ^{[14
]}

Sivananthan, Saskia ^{[15
]}

Smith, Eric E. ^{[14
]}

Soucy, Jean-Paul ^{[16
]}

Vedel, Isabelle ^{[17
]}

Gauthier, Serge ^{[18
,19
]}

机构：

[1] Univ Calgary, Hotchkiss Brain Inst & OBrien Inst Publ Hlth, Dept Psychiat, Calgary, AB, Canada

[2] Univ Toronto, Dept Med Neurol, Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada

[3] Univ Alberta, Neurosci & Mental Hlth Inst, Edmonton, AB, Canada

[4] Univ Toronto, Baycrest Hlth Sci, Toronto, ON, Canada

[5] Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada

[6] Univ Laval, Clin Interdisciplinaire Memoire, Dept Sci Neurol, CHU Quebec, Laval, PQ, Canada

[7] Univ Laval, Fac Med, Laval, PQ, Canada

[8] Univ Western Ontario, Dept Med, London, ON, Canada

[9] Univ Western Ontario, Dept Epidemiol, London, ON, Canada

[10] Univ Western Ontario, Dept Biostat, London, ON, Canada

[11] Parkwood Inst, Gait & Brain Lab, London, ON, Canada

[12] Dalhousie Univ, Halifax, NS, Canada

[13] McGill Ctr Studies Aging, Neurosurg & Psychiat, Montreal, PQ, Canada

[14] Univ Calgary, Hotchkiss Brain Inst, Calgary, AB, Canada

[15] Alzheimer Soc Canada, Toronto, ON, Canada

[16] McGill Univ, Concordia Univ, McConnell Brain Imaging Ctr, Perform Ctr,Montreal Neurol Inst, Montreal, PQ, Canada

[17] McGill Univ, Dept Family Med, Montreal, PQ, Canada

[18] McGill Ctr Studies Aging, Alzheimer Dis Res Unit, Montreal, PQ, Canada

[19] McGill Ctr Studies Aging, 6825 LaSalle Blvd, Montreal, PQ H4H 1R3, Canada

来源：

ALZHEIMERS & DEMENTIA | 2020年 / 16卷 / 08期

关键词：

MILD COGNITIVE IMPAIRMENT; SUPPORTING INFORMAL CAREGIVERS; APPROPRIATE USE CRITERIA; IMAGING TASK-FORCE; MINI-MENTAL STATE; ALZHEIMERS-DISEASE; AMYLOID PET; INSTRUMENTAL ACTIVITIES; HEALTH-CARE; GUIDELINE DEVELOPMENT;

D O I：

10.1002/alz.12105

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Since 1989, four Canadian Consensus Conferences on the Diagnosis and Treatment of Dementia (CCCDTD) have provided evidence-based dementia guidelines for Canadian clinicians and researchers. We present the results of the 5th CCCDTD, which convened in October 2019, to address topics chosen by the steering committee to reflect advances in the field, and build on previous guidelines. Topics included: (1) utility of the National Institute on Aging research framework for clinical Alzheimer's disease (AD) diagnosis; (2) updating diagnostic criteria for vascular cognitive impairment, and its management; (3) dementia case finding and detection; (4) neuroimaging and fluid biomarkers in diagnosis; (5) use of non-cognitive markers of dementia for better dementia detection; (6) risk reduction/prevention; (7) psychosocial and non-pharmacological interventions; and (8) deprescription of medications used to treat dementia. We hope the guidelines are useful for clinicians, researchers, policy makers, and the lay public, to inform a current and evidence-based approach to dementia.

引用

页码：1182 / 1195

页数：14

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