Larvicidal activity of crude extracts from Larrea cuneifolia (Zygophyllaceae) and of its metabolite nordihydroguaiaretic acid against the vector Culex quinquefasciatus (Diptera: Culicidae)

被引：7

作者：

Batallan, Gonzalo ^{[1
,2
]}

Torre, Romina ^{[1
]}

Flores, Fernando ^{[2
]}

Konigheim, Brenda ^{[2
]}

Luduena-Almeida, Francisco ^{[1
]}

Tonn, Carlos ^{[3
]}

Contigiani, Marta ^{[2
]}

Almiron, Walter ^{[1
]}

机构：

[1] Univ Nacl Cordoba, Fac Ciencias Exactas Fis & Nat, Ctr Invest Entomol Cordoba, RA-5000 Cordoba, Argentina

[2] Univ Nacl Cordoba, Fac Ciencias Med, Inst Virol Dr Jose M Vanella, RA-5000 Cordoba, Argentina

[3] Univ San Luis, Inst Invest Tecnol Quim, Fac Quim Bioquim & Farm, Area Quim Organ, San Luis, Argentina

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2013年 / 46卷 / 01期

关键词：

Larrea cuneifolia; Culex quinquefasciatus; larvicidal; AEDES-AEGYPTI; LEAF EXTRACTS; DESERT;

D O I：

10.1590/0037-868211392013

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Introduction: The aim of the present study was to analyze the larvicidal activity of different crude extracts of Larrea cuneifolia and its most abundant lignan, nordihydroguaiaretic acid (NDGA), against Culex quinquefasciatus. Methods: Chloroform, methanol, and aqueous extracts from L. cuneifolia and NDGA were tested against larvae of Cx. quinquefasciatus under laboratory conditions. Results: The chloroform extract showed the highest larvicidal effect, with an estimated LC50 of 0.062 mg/ml. NDGA also demonstrated significant larvicidal activity with an estimated LC50 of 0.092 mg/ml. Conclusions: These results indicate that the chloroform extract of L. cuneifolia and NDGA are promising insecticides of botanical origin that could be useful for controlling Cx. quinquefasciatus.

引用

页码：84 / 87

页数：4

共 15 条

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