Photoredox and cobalt co-catalyzed C(sp2)-H functionalization/C-O bond formation for synthesis of lactones under oxidant- and acceptor-free conditions

被引：55

作者：

Zhang, Muliang ^{[1
]}

Ruzi, Rehanguli ^{[1
]}

Li, Nan ^{[1
]}

Xie, Jin ^{[1
]}

Zhu, Chengjian ^{[1
,2
]}

机构：

[1] Nanjing Univ, State Key Lab Coordinat Chem, Jiangsu Key Lab Adv Organ Mat, Sch Chem & Chem Engn, Nanjing 210023, Jiangsu, Peoples R China

[2] Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2018年 / 5卷 / 05期

基金：

中国国家自然科学基金;

关键词：

HYDROGEN EVOLUTION REACTION; VISIBLE-LIGHT CATALYSIS; CARBOXYLIC-ACIDS; EXTERNAL OXIDANT; CROSS-COUPLINGS; MILD; DERIVATIVES; ACTIVATION; ARENES; LACTONIZATION;

D O I：

10.1039/c7qo00795g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical photoredox and cobalt co-catalyzed C(sp(2))-H functionalization/C-O bond formation is described herein, with dihydrogen as the only by-product. A variety of lactone products can be successfully constructed under oxidant- and acceptor-free conditions with good functional group tolerance and high yield. This protocol also provides a facile route to remote hydroxylated arenes and chromene.

引用

收藏

页码：749 / 752

页数：4

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