Visible-Light-Induced, Manganese-Catalyzed Tandem Cyclization of 2-Biphenyl Isocyanides with Cyclopropanols for the Synthesis of 6-β-Ketoalkyl Phenanthridines

被引：14
作者：
Wang, Liping [1 ,2 ]
Ding, Qiuping [1 ,2 ]
Li, Xiaofang [1 ,2 ]
Peng, Yiyuan [1 ,2 ]
机构：
[1] Jiangxi Normal Univ, Minist Educ, Key Lab Small Funct Organ Mol, Nanchang 330022, Jiangxi, Peoples R China
[2] Jiangxi Normal Univ, Jiangxis Key Lab Green Chem, Nanchang 330022, Jiangxi, Peoples R China
来源：
ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 8卷 / 03期
基金：
中国国家自然科学基金;
关键词：
isocyanides; alcohols; manganese; cyclization; visible-light; C-H ACTIVATION; OXIDATIVE CYCLIZATION; PHOTOREDOX CATALYSIS; EFFICIENT SYNTHESIS; ARYL ISONITRILES; 2-ISOCYANOBIPHENYLS; STRATEGY; DECARBOXYLATION/CYCLIZATION; ALKOXYCARBONYLATION; SILOXYCYCLOPROPANES;
D O I：
10.1002/ajoc.201800733
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A visible-light-induced, manganese-catalyzed protocol for the synthesis of 6-beta-keto alkyl phenanthridines has been developed efficiently from 2-biphenyl isocyanides and cyclopropanols in the absence of an external oxidant. This transformation is amenable to various isocyanides and tertiary cyclopropanols under catalytic amounts of Mn(acac)(3) (10 mol%).
引用
收藏
页码：385 / 390
页数：6
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