The role of retinoids in the adult nervous system and their therapeutic potential

被引：9
作者：
Christie, V. B. [1 ,2 ]
Marder, T. B. [3 ]
Whiting, A. [3 ]
Przyborski, S. A. [1 ,2 ]
机构：
[1] Univ Durham, Sch Biol & Biomed Sci, Durham DH1 3LE, England
[2] ReInnervate Ltd, Durham DH1 3HP, England
[3] Univ Durham, Dept Chem, Durham DH1 3LE, England
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2008年 / 8卷 / 06期
关键词：
vitamin A; retinoids; adult nervous system; development; neurological disorder; synthetic retinoid; therapeutics;
D O I：
10.2174/138955708784534391
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The mode of action of retinoids in relation to their activity in the adult central nervous system and the potential of synthetic retinoid analogues is reviewed. Investigation into the activity of such molecules will further our understanding of the retinoid pathway during nervous system development and in various neurological disease states.
引用
收藏
页码：601 / 608
页数：8
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