Survival among patients with dementia from a large multi-ethnic population

被引:79
作者
Waring, SC
Doody, RS
Pavlik, MN
Massman, PJ
Chan, WY
机构
[1] Univ Texas, Sch Publ Hlth, Div Epidemiol, Houston, TX 77030 USA
[2] Baylor Coll Med, Dept Neurol, Houston, TX 77030 USA
[3] Baylor Coll Med, Dept Family & Community Med, Houston, TX 77030 USA
[4] Univ Houston, Dept Psychol, Houston, TX USA
[5] Univ Texas, Sch Publ Hlth, Dept Biostat, Houston, TX USA
关键词
Alzheimer disease; dementia; survival;
D O I
10.1097/01.wad.0000189033.35579.2d
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Survival among patients with dementia is critical information needed For planning and assessing the overall impact of dementia. Attrition from longtudinal cohorts often limits the confidence in survival estimates, For this Study, we examined Survival among dementia patients from a large multi-ethnic Population with excellent longitudinal follow-up. Subjects were all Baylor Alzheimer's Disease Center patients residing in the greater Houston area at the time of initial diagnosis. Vital status was available for all subjects. We estimated median Survival time (Kaplan-Meier) from first symptom) onset and from diagnosis, and examined the effects of baseline patient characteristics on Survival. Median survival time for patients with ally form of dementia was 10.5 years from onset and 5.7 years from diagnosis. Similarly, median survival time for probable Alzheimer disease patients was 11.3 years from onset and 5.7 years from diagnosis. Significant trends of decreasing survival with increasing age group (< 70; 70-79, >= 80) were evident for all dementia patients and for patients with Alzheimer disease. Our findings are consistent with previous Studies and provide compelling evidence that survival from onset or diagnosis of dementia depends more on age than any other factor.
引用
收藏
页码:178 / 183
页数:6
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