A formal [3+2] cycloaddition for the synthesis of bicyclo[3.2.1]octanes

被引：5

作者：

Orac, Crina M. ^{[1
]}

Bergmeier, Stephen C. ^{[1
]}

机构：

[1] Ohio Univ, Clippinger Labs, Dept Chem & Biochem, Athens, OH 45701 USA

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 12期

基金：

美国国家卫生研究院;

关键词：

CHLOROSULFONYL ISOCYANATE; LEWIS-ACID; ALLYLSILANES; ANNULATION; (+/-)-PEDUNCULARINE; DERIVATIVES; HYDROXY; SILANES; ALKENES; ENE;

D O I：

10.1016/j.tetlet.2008.12.098

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new and a direct synthetic method for the construction of the bicyclo[3.2.1]octane system is envisioned by assembling cyclic allylsilanes with electron-deficient double bonds in a single step via a formal diastereoselective Lewis acid-promoted [3+2] cycloaddition. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：1261 / 1263

页数：3

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