Cancer of the gastroesophageal junction: a diagnosis, classification, and management review

被引：74

作者：

Chevallay, Mickael ^{[1
]}

Bollschweiler, Elfriede ^{[2
]}

Chandramohan, Servarayan M. ^{[3
,4
,5
]}

Schmidt, Thomas ^{[6
]}

Koch, Oliver ^{[7
]}

Demanzoni, Giovanni ^{[8
]}

Moenig, Stefan ^{[1
]}

Allum, William ^{[9
]}

机构：

[1] Geneva Univ Hosp, Visceral Surg Dept, Rue Gabrielle Perret Gentil 4, CH-1205 Geneva, Switzerland

[2] Univ Cologne, Dept Visceral & Vasc Surg, Cologne, Germany

[3] Madras Med Coll & Govt Gen Hosp, Dept Surg Gastroenterol, Chennai, Tamil Nadu, India

[4] Madras Med Coll & Govt Gen Hosp, Ctr Excellence Upper Gastro Intestinal Surg, Chennai, Tamil Nadu, India

[5] Rajiv Gandhi Govt Gen Hosp, Chennai, Tamil Nadu, India

[6] Univ Hosp Heidelberg, Dept Gen Visceral & Transplantat Surg, Heidelberg, Germany

[7] Paracelsus Med Univ, Dept Surg, Salzburg, Austria

[8] Univ Verona, Dept Gen Surg, Verona, Italy

[9] Royal Marsden Hosp, Dept Surg, London, England

来源：

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES | 2018年 / 1434卷 / 01期

关键词：

esophagectomy; minimally invasive; FLOT; PERIOPERATIVE CHEMOTHERAPY; PREOPERATIVE CHEMORADIOTHERAPY; ESOPHAGOGASTRIC JUNCTION; NEOADJUVANT CHEMOTHERAPY; SURGICAL STRATEGIES; ESOPHAGEAL CANCER; ADENOCARCINOMA; MULTICENTER; RESECTION; SURVIVAL;

D O I：

10.1111/nyas.13954

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Management of gastroesophageal junction (GEJ) adenocarcinoma is a controversial topic. The rising incidence of this cancer requires a clear consensus to ensure proper management. Application of oncological principles for tumors of the esophagus or stomach is not possible because of comparative differences in the biology of GEJ adenocarcinoma, leading to different therapeutic options. Staging work-up with endoscopy, endosonography, and PET is essential to inform the choice of neoadjuvant treatment and surgical approach to GEJ adenocarcinoma. Surgery remains the only curative treatment and should be undertaken in specialized centers.

引用

页码：132 / 138

页数：7

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