Case reports: Persistent hiccup as an atypical presentation of COVID-19 infection in a vaccinated subject

Introduction: and Importance: COVID-19 have wide array of clinical manifestation involving both respiratory and non-respiratory symptoms including neurological symptoms. Hiccups is the involuntary and spasmodic movement of the diaphragm and the intercoastal muscle that leads to the closure of the glottis and limitation of breathing in air.Case presentation: We present a case of a 72-year old SARS COV-2 positive male with hypertension who have persistent hiccup. The patient is a vaccinated subject with 2 dose of Vero cells.Clinical findings and investigations: Vitals were stable.Mild dehydration was present.Bilateral Diffuse wheeze was present on Respiratory examination. No other abnormalities were detected during systemic examination.Imaging of his chest revealed bilateral mid-lung opacities and air bronchogram.Interventions and outcome: Perisitent hiccup was treated with metoclopramide. The hiccups reduced as the patient required less oxygen supplementation and inflammatory indicators decreased.Relevance and impact: This case report tends to provide information and awareness among physicians regarding this atypical presentation of the disease.