Metabolic syndrome in vitiligo

被引:27
作者
Pietrzak, Aldona [1 ]
Bartosinska, Joanna [1 ]
Hercogova, Jana [2 ]
Lotti, Torello M. [3 ]
Chodorowska, Grazyna [1 ]
机构
[1] Med Univ, Dept Dermatol Venereol & Paediat Dermatol, PL-20080 Lublin, Poland
[2] Charles Univ Prague, Bulovka Univ Hosp, Fac Med 2, Dept Dermatol, Prague, Czech Republic
[3] Univ Rome G Marconi, Rome, Italy
关键词
metabolic abnormalities; oxidative stress; vitiligo; ADIPOSE-TISSUE; HOMOCYSTEINE; INFLAMMATION; MELANIN;
D O I
10.1111/dth.12012
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Vitiligo is an acquired, depigmenting skin disease with still unclear, multifactorial etiopathogenesis. However, there is growing evidence that vitiligo affects not only the skin but it may also be connected with metabolic abnormalities, including glucose intolerance and lipid abnormalities, all of which confirms the systemic nature of the disease. Recently, it has been shown that melanocytes, especially those found in the adipose tissue, due to their ability to decrease inflammation and oxidative damage, are capable of preventing the metabolic syndrome. The article presents updated knowledge on potential metabolic disturbances in vitiligo.
引用
收藏
页码:S41 / S43
页数:3
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