Breaking the mold: A case of pulmonary mucormycosis treated with isavuconazole

被引:4
作者
Huggins, Jonathan [1 ]
Al Jurdi, Ayman [2 ,3 ]
Gupta, Renuka [2 ,3 ]
机构
[1] Hosp Univ Penn, 3400 Spruce St, Philadelphia, PA 19104 USA
[2] Weill Cornell Med, 1300 York Ave, New York, NY 10065 USA
[3] NewYork Presbyterian Hosp, Weill Cornell Med Ctr, 525 East 68th St, New York, NY 10065 USA
关键词
Mucormycosis; Pulmonary; Infections; Isavuconazole; DIAGNOSIS;
D O I
10.1016/j.mmcr.2018.11.004
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Pulmonary mucormycosis is a rare opportunistic invasive fungal infection that disproportionately affects immunocompromised hosts and carries high morbidity and mortality. It is traditionally treated with combined pharmacologic and surgical modalities. Here we present a case of pulmonary mucormycosis in a patient whose disease burden precluded surgical management, and in whom acute kidney injury necessitated therapy with an alternative to the recommended pharmacologic antifungal therapy.
引用
收藏
页码:34 / 36
页数:3
相关论文
共 12 条
[1]  
Al-Sheikhli J., 2018, BMJ CASE REP
[2]   ESCMID† and ECMM‡ joint clinical guidelines for the diagnosis and management of mucormycosis 2013 [J].
Cornely, O. A. ;
Arikan-Akdagli, S. ;
Dannaoui, E. ;
Groll, A. H. ;
Lagrou, K. ;
Chakrabarti, A. ;
Lanternier, F. ;
Pagano, L. ;
Skiada, A. ;
Akova, M. ;
Arendrup, M. C. ;
Boekhout, T. ;
Chowdhary, A. ;
Cuenca-Estrella, M. ;
Freiberger, T. ;
Guinea, J. ;
Guarro, J. ;
de Hoog, S. ;
Hope, W. ;
Johnson, E. ;
Kathuria, S. ;
Lackner, M. ;
Lass-Floerl, C. ;
Lortholary, O. ;
Meis, J. F. ;
Meletiadis, J. ;
Munoz, P. ;
Richardson, M. ;
Roilides, E. ;
Tortorano, A. M. ;
Ullmann, A. J. ;
van Diepeningen, A. ;
Verweij, P. ;
Petrikkos, G. .
CLINICAL MICROBIOLOGY AND INFECTION, 2014, 20 :5-26
[3]   Isavuconazole in the treatment of invasive aspergillosis and mucormycosis infections [J].
Donnelley, Monica A. ;
Zhu, Elizabeth S. ;
Thompson, George R., III .
INFECTION AND DRUG RESISTANCE, 2016, 9 :79-86
[4]   Cavitary pulmonary disease [J].
Gadkowski, L. Beth ;
Stout, Jason E. .
CLINICAL MICROBIOLOGY REVIEWS, 2008, 21 (02) :305-+
[5]   Pulmonary mucormycosis - The last 30 years [J].
Lee, FYW ;
Mossad, SB ;
Adal, KA .
ARCHIVES OF INTERNAL MEDICINE, 1999, 159 (12) :1301-1309
[6]   Diagnosis and treatment of pulmonary mucormycosis: A case report [J].
Luo, Zhiming ;
Zhang, Lin .
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 14 (04) :3788-3791
[7]   Isavuconazole treatment for mucormycosis: a single-arm open-label trial and case-control analysis [J].
Marty, Francisco M. ;
Ostrosky-Zeichner, Luis ;
Cornely, Oliver A. ;
Mullane, Kathleen M. ;
Perfect, John R. ;
Thompson, George R., III ;
Alangaden, George J. ;
Brown, Janice M. ;
Fredricks, David N. ;
Heinz, Werner J. ;
Herbrecht, Raoul ;
Klimko, Nikolai ;
Klyasova, Galina ;
Maertens, Johan A. ;
Melinkeri, Sameer R. ;
Oren, Ilana ;
Pappas, Peter G. ;
Racil, Zdenek ;
Rahav, Galia ;
Santos, Rodrigo ;
Schwartz, Stefan ;
Vehreschild, J. Janne ;
Young, Jo-Anne H. ;
Chetchotisakd, Ploenchan ;
Jaruratanasirikul, Sutep ;
Kanj, Souha S. ;
Engelhardt, Marc ;
Kaufh, Achim ;
Ito, Masanori ;
Lee, Misun ;
Sasse, Carolyn ;
Maher, Rochelle M. ;
Zeiher, Bernhardt ;
Vehreschild, Maria J. G. T. .
LANCET INFECTIOUS DISEASES, 2016, 16 (07) :828-837
[8]  
Roden M. M., 2005, CLIN INFECT DIS, V41, P634
[9]   Solitary pulmonary nodule: A rare presentation of pulmonary mucormycosis in an immunocompetent adult [J].
Sarkar, Supriya ;
Jash, Debraj ;
Maji, Arnab ;
Maikap, Malay Kr .
LUNG INDIA, 2014, 31 (01) :70-72
[10]   Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007 [J].
Skiada, A. ;
Pagano, L. ;
Groll, A. ;
Zimmerli, S. ;
Dupont, B. ;
Lagrou, K. ;
Lass-Florl, C. ;
Bouza, E. ;
Klimko, N. ;
Gaustad, P. ;
Richardson, M. ;
Hamal, P. ;
Akova, M. ;
Meis, J. F. ;
Rodriguez-Tudela, J. -L. ;
Roilides, E. ;
Mitrousia-Ziouva, A. ;
Petrikkos, G. .
CLINICAL MICROBIOLOGY AND INFECTION, 2011, 17 (12) :1859-1867