Sertoli Cell Quiescence - New Insights

被引：18
作者：
Hayrabedyan, Soren [1 ]
Todorova, Krassimira [1 ]
Pashova, Shina [1 ]
Mollova, Margarita [1 ]
Fernandez, Nelson [2 ]
机构：
[1] BAS, Inst Biol & Immunol Reprod, Sofia 1113, Bulgaria
[2] Univ Essex, Sch Biol Sci, Colchester CO4 3SQ, Essex, England
来源：
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 2012年 / 68卷 / 06期
关键词：
Cell quiescence; Sertoli cells; stemness; TESTICULAR DYSGENESIS SYNDROME; FETAL LEYDIG-CELLS; HUMAN TESTIS; ID PROTEINS; MALE GERM; MOUSE; PROLIFERATION; EXPRESSION; MICE; SPERMATOGENESIS;
D O I：
10.1111/j.1600-0897.2012.01137.x
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
It is currently accepted that the Sertoli cells are proliferatively active only during the embryogenesis and early fetal development, seizing to divide after puberty, when the spermatogenic niche is prepared, and they become terminally differentiated. So far, only seasonal breeders from mammals have been reported as having season-dependent variations in adult Sertoli cells number and proliferation activity. In this review, we will try to shed light on testis somatic cell plasticity and discuss new evidence for some unique proliferative features Sertoli cells harbor.
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收藏
页码：451 / 455
页数：5
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