Effects of green tea extract epigallocatechin-3-gallate (EGCG) on oral disease-associated microbes: a review

被引:29
作者
Kong, Chen [1 ]
Zhang, Huili [1 ]
Li, Lingfeng [1 ]
Liu, Zhihui [1 ]
机构
[1] Jilin Univ, Hosp Stomatol, Changchun, Jilin, Peoples R China
关键词
Epigallocatechin-3-gallate; green tea; anti-infective properties; dental caries; periodontosis; PORPHYROMONAS-GINGIVALIS; STREPTOCOCCUS-MUTANS; PERIODONTAL-DISEASE; DENTAL-CARIES; IN-VITRO; BIOFILM FORMATION; GALLATE; CATECHIN; POLYPHENOLS; INHIBITION;
D O I
10.1080/20002297.2022.2131117
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
For thousands of years, caries, periodontitis and mucosal diseases, which are closely related to oral microorganisms, have always affected human health and quality of life. These complex microbiota present in different parts of the mouth can cause chronic infections in the oral cavity under certain conditions, some of which can also lead to acute and systemic diseases. With the mutation of related microorganisms and the continuous emergence of drug-resistant strains, in order to prevent and treat related diseases, in addition to the innovation of diagnosis and treatment technology, the development of new antimicrobial drugs is also important. Catechins are polyphenolic compounds in green tea, some of which are reported to provide health benefits for a variety of diseases. Studies have shown that epigallocatechin-3-gallate (EGCG) is the most abundant and effective active ingredient in green tea catechins, which acts against a variety of gram-positive and negative bacteria, as well as some fungi and viruses. This review aims to summarize the research progress on the activity of EGCG against common oral disease-associated organisms and discuss the mechanisms of these actions, hoping to provide new medication strategies for the prevention and treatment of oral infectious diseases, the future research of EGCG and its translation into clinical practice are also discussed.
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页数:14
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共 141 条
[1]   Anti-plaque effect of a synergistic combination of green tea and Salvadora persica L. against primary colonizers of dental plaque [J].
Abdulbaqi, Hayder Raad ;
Himratul-Aznita, Wan Harun ;
Baharuddin, Nor Adinar .
ARCHIVES OF ORAL BIOLOGY, 2016, 70 :117-124
[2]   Variations of Porphyromonas gingivalis fimbriae in relation to microbial pathogenesis [J].
Amano, A ;
Nakagawa, I ;
Okahashil, N ;
Hamada, N .
JOURNAL OF PERIODONTAL RESEARCH, 2004, 39 (02) :136-142
[3]  
Anita P, 2014, J Basic Clin Pharm, V6, P35, DOI 10.4103/0976-0105.145777
[4]   Inhibitory Activity of Green Tea (Camellia sinensis) Extract on Some Clinically Isolated Cariogenic and Periodontopathic Bacteria [J].
Araghizadeh, Abdolmehdi ;
Kohanteb, Jamshid ;
Fani, Mohammad Mehdi .
MEDICAL PRINCIPLES AND PRACTICE, 2013, 22 (04) :368-372
[5]   Role of hydrogen peroxide in bactericidal action of catechin [J].
Arakawa, H ;
Maeda, M ;
Okubo, S ;
Shimamura, T .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2004, 27 (03) :277-281
[6]   Effects of the tea catechin epigallocatechin gallate on Porphyromonas gingivalis biofilms [J].
Asahi, Y. ;
Noiri, Y. ;
Miura, J. ;
Maezono, H. ;
Yamaguchi, M. ;
Yamamoto, R. ;
Azakami, H. ;
Hayashi, M. ;
Ebisu, S. .
JOURNAL OF APPLIED MICROBIOLOGY, 2014, 116 (05) :1164-1171
[7]   Herpes simplex virus resistance to acyclovir and penciclovir after two decades of antiviral therapy [J].
Bacon, TH ;
Levin, MJ ;
Leary, JJ ;
Sarisky, RT ;
Sutton, D .
CLINICAL MICROBIOLOGY REVIEWS, 2003, 16 (01) :114-+
[8]   Adaptation of salivary Lactobacillus strains to xylitol [J].
Badet, C ;
Richard, B ;
Castaing-Debat, M ;
de Flaujac, PM ;
Dorignac, G .
ARCHIVES OF ORAL BIOLOGY, 2004, 49 (02) :161-164
[9]   Antimicrobial activity of tea catechin against canine oral bacteria and the functional mechanisms [J].
Bai, Lanlan ;
Takagi, Shiaki ;
Ando, Tasuke ;
Yoneyama, Hiroshi ;
Ito, Kumiko ;
Mizugai, Hiroyuki ;
Isogai, Emiko .
JOURNAL OF VETERINARY MEDICAL SCIENCE, 2016, 78 (09) :1439-1445
[10]   Synergistic effects of tea polyphenol epigallocatechin 3-O-gallate and azole drugs against oral Candida isolates [J].
Behbehani, J. M. ;
Irshad, M. ;
Shreaz, S. ;
Karched, M. .
JOURNAL DE MYCOLOGIE MEDICALE, 2019, 29 (02) :158-167