Hydrocarbon-induced hormesis: 101 years of evidence at the margin?

被引：27

作者：

Agathokleous, Evgenios ^{[1
]}

Barcelo, Damia ^{[2
,3
]}

Tsatsakis, Aristidis ^{[4
]}

Calabrese, Edward J. ^{[5
]}

机构：

[1] Nanjing Univ Informat Sci & Technol NUIST, Sch Appl Meteorol, Inst Ecol, Key Lab Agrometeorol Jiangsu Prov, Ningliu Rd 219, Nanjing 210044, Jiangsu, Peoples R China

[2] IDAEA CSIC, Inst Environm Assessment & Water Res, C Jordi Girona 18-26, Barcelona 08034, Spain

[3] ICRA, Catalan Inst Water Res, Emili Grahit 101, Girona 17003, Spain

[4] Univ Crete, Med Sch, Lab Toxicol, Iraklion, Greece

[5] Univ Massachusetts, Dept Environm Hlth Sci, Morrill 1,N344, Amherst, MA 01003 USA

来源：

ENVIRONMENTAL POLLUTION | 2020年 / 265卷

关键词：

Dose-response relationship; Environmental pollution; Global environmental change; Hormesis; Hydrocarbon contamination; Organismic stress; POLYCYCLIC AROMATIC-HYDROCARBONS; ECOLOGICAL RISK-ASSESSMENT; HORMETIC DOSE RESPONSES; GROWTH; EXPOSURE; STIMULATION; GERMINATION; SEDIMENTS; POLLUTION; MIXTURES;

D O I：

10.1016/j.envpol.2020.114846

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Hydrocarbons are used worldwide for an array of purposes ranging from transportation to making plastics and synthetic fibers. Hydrocarbons pollution can occur from local to global scales, becoming a focus of regulatory authorities since a long time ago. While studies show numerous adverse effects on biota, such effects usually occur at very high doses. This paper collates significant evidence showing that hydrocarbons induce hormesis in biota, with dual effects of low versus high doses. Hydrocarbon-induced hormetic responses should be considered in relevant dose-response studies as well as in risk assessment. Dismissing hormesis could lead to incorrect predictions of hydrocarbons effects, which can occur at doses up to 100 times smaller than the traditional toxicological threshold, and would raise serious concerns regarding human and ecological health safety. (C) 2020 Elsevier Ltd. All rights reserved.

引用

页数：4

共 65 条

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