Endothelial-to-mesenchymal transition in multiple sclerosis: Good cells gone bad

被引：1

作者：

Mey, Gabrielle M. ^{[1
,2
]}

DeSilva, Tara M. ^{[1
,2
]}

机构：

[1] Cleveland Clin Fdn, Lerner Res Inst, Dept Neurosci, Cleveland, OH 44195 USA

[2] Case Western Reserve Univ, Cleveland, OH 44106 USA

来源：

NEURON | 2022年 / 110卷 / 19期

关键词：

D O I：

10.1016/j.neuron.2022.09.017

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In cancer and cardiovascular disease, endothelial cells can transform into mesenchymal cells (EndoMT), affecting disease onset and progression. In this issue of Neuron, Sun et al. (2022) demonstrate how EndoMT triggers breakdown of the blood-CNS barrier in the pathogenesis of multiple sclerosis.

引用

页码：3053 / 3055

页数：3

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