Ventricular arrhythmias and sudden cardiac death

被引:211
作者
John, Roy M. [1 ]
Tedrow, Usha B. [1 ]
Koplan, Bruce A. [1 ]
Albert, Christine M. [1 ]
Epstein, Laurence M. [1 ]
Sweeney, Michael O. [1 ]
Miller, Amy Leigh [1 ]
Michaud, Gregory F. [1 ]
Stevenson, William G. [1 ]
机构
[1] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Med,Div Cardiol,Cardiac Arrhythmia Serv, Boston, MA 02115 USA
关键词
IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR; ASSOCIATION TASK-FORCE; GUIDELINES WRITING COMMITTEE; CATHETER ABLATION; MYOCARDIAL-INFARCTION; HYPERTROPHIC CARDIOMYOPATHY; AMERICAN-COLLEGE; HEART-DISEASE; RESYNCHRONIZATION THERAPY; PROPHYLACTIC IMPLANTATION;
D O I
10.1016/S0140-6736(12)61413-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Management strategies for ventricular arrhythmias are guided by the risk of sudden death and severity of symptoms. Patients with a substantial risk of sudden death usually need an implantable cardioverter defibrillator (ICD). Although ICDs effectively end most episodes of ventricular tachycardia or ventricular fibrillation and decrease mortality in specific populations of patients, they have inherent risks and limitations. Generally, antiarrhythmic drugs do not provide sufficient protection from sudden death, but do have a role in reducing arrhythmias that cause symptoms. Catheter ablation is likewise important for reducing the frequency of spontaneous arrhythmias and is curative for some patients, usually those with idiopathic arrhythmias and no heart disease. Arrhythmia surgery is now infrequent, offered by only a few specialised centres for refractory arrhythmias. Advances in understanding of genetic arrhythmia syndromes and in technology for mapping and ablation of ventricular arrhythmias, and enhanced algorithms in implantable devices for rhythm management, have contributed to improved outcomes.
引用
收藏
页码:1520 / 1529
页数:10
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