Dyslipidemia Profiles in Patients with Peripheral Artery Disease

被引：31

作者：

Aday, Aaron W. ^{[1
]}

Everett, Brendan M. ^{[2
,3
]}

机构：

[1] Vanderbilt Univ, Dept Med, Vanderbilt Translat & Clin Cardiovasc Res Ctr, Div Cardiovasc Med,Med Ctr, 2525 West End Ave,Suite 300, Nashville, TN 37203 USA

[2] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA

[3] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Cardiovasc Med, Boston, MA 02115 USA

来源：

CURRENT CARDIOLOGY REPORTS | 2019年 / 21卷 / 06期

关键词：

Dyslipidemia; Lipoproteins; Atherosclerosis; Cholesterol; Apolipoproteins; Peripheral artery disease; CARDIOVASCULAR RISK-FACTORS; DENSITY-LIPOPROTEIN CHOLESTEROL; CORONARY-HEART-DISEASE; INTERMITTENT CLAUDICATION; VASCULAR-DISEASE; FEMORAL ATHEROSCLEROSIS; SMOKING; APOLIPOPROTEINS; PROGRESSION; PREVALENCE;

D O I：

10.1007/s11886-019-1129-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose of ReviewThis review of the literature aims to discuss the evidence linking different lipid and apolipoprotein measures to peripheral artery disease.Recent FindingsMeasures of atherogenic dyslipidemia, including elevations in total cholesterol and total cholesterol/high-density lipoprotein cholesterol as well as low levels of high-density lipoprotein cholesterol, are strongly associated with future risk of peripheral artery disease. Compared to coronary artery disease, there are fewer data showing an association between low-density lipoprotein cholesterol and future risk of peripheral artery disease. Novel lipid measures, including nuclear magnetic resonance-derived lipoproteins and oxidized lipids, may lead to better assessments of future peripheral artery disease risk.SummaryThese data highlight the important differences between lipid risk factors for peripheral and coronary artery disease. Improved understanding of these distinctions may lead to new therapeutic options for patients with peripheral artery disease.

引用

页数：9

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