Liquid biopsy: novel technologies and clinical applications

被引：36

作者：

Reimers, Natalie ^{[2
]}

Pantel, Klaus ^{[1
]}

机构：

[1] Univ Med Ctr Hamburg Eppendorf, Dept Tumor Biol, Martinistr 52, D-20246 Hamburg, Germany

[2] Univ Med Ctr Hamburg Eppendorf, Dept Tumor Biol, Hamburg, Germany

来源：

CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 2019年 / 57卷 / 03期

关键词：

circulating tumor cells; liquid biopsy; minimal residual disease; CIRCULATING TUMOR-CELLS; BREAST-CANCER PATIENTS; POOLED ANALYSIS; EDUCATED PLATELETS; IDENTIFICATION; EXOSOMES; CHALLENGES; DNA;

D O I：

10.1515/cclm-2018-0610

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

"Liquid biopsy" was introduced as a new diagnostic concept in 2010 for the analysis of circulating tumor cells (CTCs) and has been now extended to material (in particular DNA) released by tumor cells in the peripheral blood of cancer patients. Over the past decade, various methods have been developed to detect CTCs and ctDNA in the peripheral blood of cancer patients.

引用

页码：312 / 316

页数：5

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