Quantification of hepatitis B virus HBsAg: clinical implications

被引：5
作者：
Buti, Maria [1 ,3 ]
Rodriguez Frias, Francisco [2 ,3 ]
Esteban, Rafael [1 ,3 ]
机构：
[1] Hosp Univ Vall dHebron, Serv Hepatol, Barcelona, Spain
[2] Hosp Univ Vall dHebron, Serv Bioquim, Barcelona, Spain
[3] Inst Carlos III, CIBEREHD, Barcelona, Spain
来源：
MEDICINA CLINICA | 2012年 / 138卷 / 11期
关键词：
Hepatitis B; Antiviral therapy; HBsAg; SURFACE-ANTIGEN DECLINE; HBV DNA LEVELS; NATURAL-HISTORY; PEGINTERFERON ALPHA-2A; SUSTAINED RESPONSE; POSITIVE PATIENTS; VIRAL LOAD; HBEAG; PREDICTION; PROTEINS;
D O I：
10.1016/j.medcli.2011.04.024
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The surface antigen of hepatitis B virus (HBsAg) is the main serological marker of HBV infection since its discovery almost 50 years ago. Currently the quantification of HBsAg has acquired special relevance as there are commercial tests to measure its levels. Several studies have shown that in patients treated with pegylated interferon alfa the fall of HBsAg levels predicts the loss of HBsAg and persistent virologic response. The role of the quantification of HBsAg in the treatment with nucleoside analogues is still not well understood and requires further studies. (C) 2011 Elsevier Espana, S.L. All rights reserved.
引用
收藏
页码：483 / 488
页数：6
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