Molecular growth algorithm based in silico high-throughput screening approach in CONTOURO used to identify inhibitors of 11b-hydroxysteroid dehydrogenase type 1

被引：0

作者：

Liu, Zhijie ^{[1
]}

Lindblom, Peter ^{[1
]}

Ye, Yuanjie ^{[1
]}

Tice, Colin ^{[3
]}

Zhuang, Linghang ^{[3
]}

Zhao, Wei ^{[3
]}

Leftheris, Katerina ^{[3
]}

Kruk, Barbara ^{[2
]}

Krosky, Paula ^{[2
]}

Lala, Deepak ^{[2
]}

McGeehan, Gerard ^{[2
]}

Claremon, David ^{[1
,3
]}

Gregg, Richard ^{[1
,2
,3
]}

Singh, Suresh B. ^{[1
]}

机构：

[1] Vitae Pharmaceut, Computat Drug Design, Ft Washington, PA 19034 USA

[2] Vitae Pharmaceut, Biol, Ft Washington, PA 19034 USA

[3] Vitae Pharmaceut, Med Chem, Ft Washington, PA 19034 USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 243卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

296-COMP

引用

页数：1

共 37 条

[21] A cell-based high-throughput assay to identify inhibitors of Organic Anion Transporting Polypeptides 1B1 and 1B3 [J].

Obaidat, Amanda ;

Gui, Chunshan ;

Chaguturu, Rathnam ;

Hagenbuch, Bruno .

FASEB JOURNAL, 2009, 23

[22] Molecular Modeling Studies of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors through Receptor-Based 3D-QSAR and Molecular Dynamics Simulations [J].

Qian, Haiyan ;

Chen, Jiongjiong ;

Pan, Youlu ;

Chen, Jianzhong .

MOLECULES, 2016, 21 (09)

[23] Identification of Important Chemical Features of 11β-Hydroxysteroid Dehydrogenase Type1 Inhibitors: Application of Ligand Based Virtual Screening and Density Functional Theory [J].

Sakkiah, Sugunadevi ;

Meganathan, Chandrasekaran ;

Sohn, Young-Sik ;

Namadevan, Sundaraganesan ;

Lee, Keun Woo .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2012, 13 (04) :5138-5162

[24] Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics [J].

Zhang, Wen ;

Hu, Xiaohui ;

Chakravarty, Harapriya ;

Yang, Zheng ;

Tam, Kin Yip .

ACS COMBINATORIAL SCIENCE, 2018, 20 (11) :660-671

[25] A novel, non-substrate-based series of glycine type 1 transporter inhibitors derived from high-throughput screening [J].

Lowe, J. ;

Drozda, S. ;

Qian, W. ;

Peakman, M. -C. ;

Liu, J. ;

Gibbs, J. ;

Harms, J. ;

Schmidt, C. ;

Fisher, K. ;

Strick, C. ;

Schmidt, A. ;

Vanase, M. ;

Lebel, L. .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (06) :1675-1678

[26] A high-throughput molecular dynamics screening (HTMDS) approach to the design of novel cyclopeptide inhibitors of ATAD2B based on the non-canonical combinatorial library [J].

Chen, Zhidong ;

Li, Yongxiao ;

Wang, Xinpei ;

Qiu, Xiaohui ;

Wang, Chenglin ;

Wang, Zhe ;

Chen, Xu ;

Wang, Junqing .

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 42 (06) :2809-2824

[27] A cell-based high-throughput screening system to identify inhibitors of the VirB8 type IV secretion system component from Brucella suis [J].

Paschos, A. ;

Sivanesan, D. ;

Baron, C. .

BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE, 2008, 86 (02) :201-201

[28] Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma [J].

Liang, Xuewu ;

Sun, Chenxia ;

Li, Chunpu ;

Yu, Haolan ;

Wei, Xiaohui ;

Liu, Xuyi ;

Bao, Wei ;

Shi, Yuqiang ;

Sun, Xiaochen ;

Khamrakulov, Mirzadavlat ;

Yang, Chenghua ;

Liu, Hong .

JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (13) :9217-9237

[29] A cell-based high-throughput screening approach for the discovery of new inhibitors of the influenza H5N1 virus [J].

Severson, William ;

Maddry, Joseph ;

Chen, Xi ;

Ananthan, Subramaniam ;

Poffenberger, Adrian ;

Rasumussen, Lynn ;

Sosa, Melinda ;

White, Lucile ;

Noah, Diana ;

Piazza, Gary .

ANTIVIRAL RESEARCH, 2008, 78 (02) :A48-A48

[30] Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well [J].

Mondal, Rubina ;

Koev, Gennadiy ;

Pilot-Matias, Tami ;

He, Yupeng ;

Ng, Teresa ;

Kati, Warren ;

Molla, Akhteruzzaman .

ANTIVIRAL RESEARCH, 2009, 82 (01) :82-88

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