Mitotic chromosome condensation

被引：279
作者：
Koshland, D
Strunnikov, A
机构：
[1] Department of Embryology, Carnegie Institution of Washington, Baltimore, MD 21210
来源：
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY | 1996年 / 12卷
关键词：
chromosome structure; mitosis; topoisomerase II; SMC proteins;
D O I：
10.1146/annurev.cellbio.12.1.305
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
In this chapter, we review the structure and composition of interphase and mitotic chromosomes. We discuss how these observations support the model that mitotic condensation is a deterministic process leading to the invariant folding of a given chromosome. The structural studies have also placed constraints on the mechanism of condensation and defined several activities needed to mediate condensation. In the context of these activities and structural information, we present our current understanding of the role of cis sites, histones, topoisomerase II, and SMC proteins in condensation. We conclude by using our current knowledge of mitotic condensation to address the differences in chromosome condensation observed from bacteria to humans and to explore the relevance of this process to other processes such as gene expression.
引用
收藏
页码：305 / 333
页数：29
相关论文
共 112 条
[1]   CHROMOSOME ASSEMBLY INVITRO - TOPOISOMERASE-II IS REQUIRED FOR CONDENSATION [J].
ADACHI, Y ;
LUKE, M ;
LAEMMLI, UK .
CELL, 1991, 64 (01) :137-148
[2]   THE ROLE OF TOPOISOMERASE-IV IN PARTITIONING BACTERIAL REPLICONS AND THE STRUCTURE OF CATENATED INTERMEDIATES IN DNA-REPLICATION [J].
ADAMS, DE ;
SHEKHTMAN, EM ;
ZECHIEDRICH, EL ;
SCHMID, MB ;
COZZARELLI, NR .
CELL, 1992, 71 (02) :277-288
[3]   ROLE OF NONHISTONE PROTEINS IN METAPHASE CHROMOSOME STRUCTURE [J].
ADOLPH, KW ;
CHENG, SM ;
LAEMMLI, UK .
CELL, 1977, 12 (03) :805-816
[4]   ANALYSIS OF WILD-TYPE AND RAD50 MUTANTS OF YEAST SUGGESTS AN INTIMATE-RELATIONSHIP BETWEEN MEIOTIC CHROMOSOME SYNAPSIS AND RECOMBINATION [J].
ALANI, E ;
PADMORE, R ;
KLECKNER, N .
CELL, 1990, 61 (03) :419-436
[5]  
ALBERTS BM, 1984, COLD SPRING HARB SYM, V49, P1
[6]   INVITRO CATENATION AND DECATENATION OF DNA AND A NOVEL EUKARYOTIC ATP-DEPENDENT TOPOISOMERASE [J].
BALDI, MI ;
BENEDETTI, P ;
MATTOCCIA, E ;
TOCCHINIVALENTINI, GP .
CELL, 1980, 20 (02) :461-467
[7]   GENES OCCUPY A FIXED AND SYMMETRICAL POSITION ON SISTER CHROMATIDS [J].
BAUMGARTNER, M ;
DUTRILLAUX, B ;
LEMIEUX, N ;
LILIENBAUM, A ;
PAULIN, D ;
VIEGASPEQUIGNOT, E .
CELL, 1991, 64 (04) :761-766
[8]   ISOLATION, CHARACTERIZATION, AND STRUCTURE OF FOLDED INTERPHASE GENOME OF DROSOPHILA-MELANOGASTER [J].
BENYAJATI, C ;
WORCEL, A .
CELL, 1976, 9 (03) :393-407
[9]   Structure and mechanism of DNA topoisomerase II [J].
Berger, JM ;
Gamblin, SJ ;
Harrison, SC ;
Wang, JC .
NATURE, 1996, 379 (6562) :225-232
[10]   THE RAD21 GENE-PRODUCT OF SCHIZOSACCHAROMYCES-POMBE IS A NUCLEAR, CELL-CYCLE-REGULATED PHOSPHOPROTEIN [J].
BIRKENBIHL, RP ;
SUBRAMANI, S .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (13) :7703-7711
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