Fueling fibrosis in chronic hepatitis C

被引：15

作者：

Bataller, Ramon ^{[2
]}

Lemon, Stanley M. ^{[1
,3
]}

机构：

[1] Univ N Carolina, Ctr Gastrointestinal Biol & Dis, Dept Med, Div Infect Dis, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Ctr Gastrointestinal Biol & Dis, Dept Med & Nutr, Div Gastroenterol & Hepatol, Chapel Hill, NC 27599 USA

[3] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2012年 / 109卷 / 36期

关键词：

STELLATE CELLS; UNITED-STATES; VIRUS CORE; PROGRESSION; EXPRESSION; CIRRHOSIS; DISEASE;

D O I：

10.1073/pnas.1212048109

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：14293 / 14294

页数：2

共 17 条

[1]

Altevogt BM, 2011, CHIMPANZEES IN BIOMEDICAL AND BEHAVIORAL RESEARCH: ASSESSING THE NECESSITY, P1

[2] Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells [J].

Bataller, R ;

Paik, YH ;

Lindquist, JN ;

Lemasters, JJ ;

Brenner, DA .

GASTROENTEROLOGY, 2004, 126 (02) :529-540

[3] Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C [J].

Colmenero, Jordi ;

Bataller, Ramon ;

Sancho-Bru, Pau ;

Dominguez, Marlene ;

Moreno, Montserrat ;

Forns, Xavier ;

Bruguera, Miquel ;

Arroyo, Vicente ;

Brenner, David A. ;

Gines, Pere .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2009, 297 (04) :G726-G734

[4] Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression [J].

Davis, Gary L. ;

Alter, Miriam J. ;

El-Serag, Hashem ;

Poynard, Thierry ;

Jennings, Linda W. .

GASTROENTEROLOGY, 2010, 138 (02) :513-U141

[5] Profibrogenic chemokines and viral evolution predict rapid progression of hepatitis C to cirrhosis [J].

Farci, Patrizia ;

Wollenberg, Kurt ;

Diaz, Giacomo ;

Engle, Ronald E. ;

Lai, Maria Eliana ;

Klenerman, Paul ;

Purcell, Robert H. ;

Pybus, Oliver G. ;

Alter, Harvey J. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (36) :14562-14567

[6] Diagnosis, Management, and Treatment of Hepatitis C: An Update [J].

Ghany, Marc G. ;

Strader, Doris B. ;

Thomas, David L. ;

Seeff, Leonard B. .

HEPATOLOGY, 2009, 49 (04) :1335-1374

[7] HUMORAL IMMUNE-RESPONSE TO HYPERVARIABLE REGION-1 OF THE PUTATIVE ENVELOPE GLYCOPROTEIN (GP70) OF HEPATITIS-C VIRUS [J].

KATO, N ;

SEKIYA, H ;

OOTSUYAMA, Y ;

NAKAZAWA, T ;

HIJIKATA, M ;

OHKOSHI, S ;

SHIMOTOHNO, K .

JOURNAL OF VIROLOGY, 1993, 67 (07) :3923-3930

[8] Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production [J].

Korenaga, M ;

Wang, T ;

Li, YC ;

Showalter, LA ;

Chan, TS ;

Sun, JR ;

Weinman, SA .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (45) :37481-37488

[9]

Kwong JC, 2012, PLOS ONE IN PRESS

[10] Visualizing Hepatitis C Virus Infections in Human Liver by Two-Photon Microscopy [J].

Liang, Yuqiong ;

Shilagard, Tuya ;

Xiao, Shu-Yuan ;

Snyder, Ned ;

Lau, Daryl ;

Cicalese, Luca ;

Weiss, Heidi ;

Vargas, Gracie ;

Lemon, Stanley M. .

GASTROENTEROLOGY, 2009, 137 (04) :1448-1458

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