Cognitive impairments in alcohol-dependent subjects

被引:174
作者
Bernardin, Florent [1 ,2 ]
Maheut-Bosser, Anne [1 ]
Paille, Francois [1 ,2 ]
机构
[1] CHU Nancy, Serv Addictol, Vandoeuvre Les Nancy, France
[2] Univ Lorraine, Fac Med, Nancy, France
来源
FRONTIERS IN PSYCHIATRY | 2014年 / 5卷
关键词
alcohol-dependence; brain atrophy; cognitive impairments; inhibition; working memory; implicit cognition; cognitive remediation therapy;
D O I
10.3389/fpsyt.2014.00078
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Chronic excessive alcohol consumption induces cognitive impairments mainly affecting executive functions, episodic memory, and visuospatial capacities related to multiple brain lesions. These cognitive impairments not only determine everyday management of these patients, but also impact on the efficacy of management and may compromise the abstinence prognosis. Maintenance of lasting abstinence is associated with cognitive recovery in these patients, but some impairments may persist and interfere with the good conduct and the efficacy of management. It therefore appears essential to clearly define neuropsychological management designed to identify and evaluate the type and severity of alcohol-related cognitive impairments. It is also essential to develop cognitive remediation therapy so that the patient can fully benefit from the management proposed in addiction medicine units.
引用
收藏
页数:6
相关论文
共 88 条
[1]   Hippocampal volume in patients with alcohol dependence [J].
Agartz, I ;
Momenan, R ;
Rawlings, RR ;
Kerich, MJ ;
Hommer, DW .
ARCHIVES OF GENERAL PSYCHIATRY, 1999, 56 (04) :356-363
[2]   MR volumetry during acute alcohol withdrawal and abstinence: A descriptive study [J].
Agartz, I ;
Brag, S ;
Franck, J ;
Hammarberg, A ;
Okugawa, G ;
Svinhufvud, K ;
Bergman, H .
ALCOHOL AND ALCOHOLISM, 2003, 38 (01) :71-78
[3]   Cognitive rehabilitation of chronic alcohol abusers [J].
Allen, DN ;
Goldstein, G ;
Seaton, BE .
NEUROPSYCHOLOGY REVIEW, 1997, 7 (01) :21-39
[4]   The process of relapse in severely dependent male problem drinkers [J].
Allsop, S ;
Saunders, B ;
Phillips, M .
ADDICTION, 2000, 95 (01) :95-106
[5]  
[Anonymous], 2006, Handbook of implicit cognition and addiction
[6]   Manifestations of early brain recovery associated with abstinence from alcoholism [J].
Bartsch, Andreas J. ;
Homola, Gyorgy ;
Biller, Armin ;
Smith, Stephen M. ;
Weijers, Heinz-Gerd ;
Wiesbeck, Gerhard A. ;
Jenkinson, Mark ;
Stefano, Nicola De ;
Solymosi, Laszlo ;
Bendszus, Martin .
BRAIN, 2007, 130 :36-47
[7]   A Role for Cognitive Rehabilitation in Increasing the Effectiveness of Treatment for Alcohol Use Disorders [J].
Bates, Marsha E. ;
Buckman, Jennifer F. ;
Nguyen, Tam T. .
NEUROPSYCHOLOGY REVIEW, 2013, 23 (01) :27-47
[8]   Short-term neuropsychological recovery in clients with substance use disorders [J].
Bates, ME ;
Voelbel, GT ;
Buckman, JF ;
Labouvie, EW ;
Barry, D .
ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH, 2005, 29 (03) :367-377
[9]  
Bendszus M, 2001, AM J NEURORADIOL, V22, P1926
[10]   Hippocampus volume loss due to chronic heavy drinking [J].
Beresford, Thomas P. ;
Arciniegas, David B. ;
Alfers, Julie ;
Clapp, Lori ;
Martin, Brandon ;
Liu, Yiping Du Dengfeng ;
Shen, Dinggang ;
Davatzikos, Christos .
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2006, 30 (11) :1866-1870