Pre- and Post-Natal Treatment of Hemophagocytic Lymphohistiocytosis

被引：8

作者：

Shah, Ami J. ^{[1
,2
,3
]}

Kapoor, Neena ^{[2
,3
]}

Cooper, Robert M. ^{[4
]}

Crooks, Gay M. ^{[2
,3
]}

Lenarsky, Carl ^{[5
]}

Abdel-Azim, Hisham ^{[2
,3
]}

Wu, Shi Qi ^{[6
,7
]}

Wilson, Kathy

Weinberg, Kenneth I. ^{[8
]}

Parkman, Robertson ^{[2
,3
]}

Kohn, Donald B. ^{[2
,3
]}

机构：

[1] Childrens Hosp Los Angeles, Div Res Immunol Bone Marrow Transplantat, Los Angeles, CA 90027 USA

[2] Univ So Calif, Keck Sch Med, Dept Pediat, Los Angeles, CA 90033 USA

[3] Childrens Hosp Los Angeles, Saban Res Inst, Los Angeles, CA 90027 USA

[4] Kaiser Permanente Med Ctr, Los Angeles, CA 90034 USA

[5] Med City Childrens Hosp, Dallas, TX USA

[6] Univ So Calif, Keck Sch Med, Dept Pathol, Los Angeles, CA 90033 USA

[7] Univ So Calif, Keck Sch Med, Dept Genet, Los Angeles, CA 90033 USA

[8] Lucille Packard Childrens Hosp, Div Pediat Stem Cell Transplantat, Palo Alto, CA USA

来源：

PEDIATRIC BLOOD & CANCER | 2009年 / 52卷 / 01期

关键词：

hematopoietic stem cell transplantation; hemophagacytic lymphohistiocytosis; in utero chemotherapy; BONE-MARROW-TRANSPLANTATION; BREAST-CANCER; PREGNANCY; CHEMOTHERAPY; EXPERIENCE;

D O I：

10.1002/pbc.21778

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hemophagocytic lymphohistiocytosis (HLH) is a rare autosomal recessive disorder of infancy and childhood that is invariably fatal if not treated. We report on the first patient to receive post-natal HSCT for HLH after receiving in utero chemotherapy for disease stabilization. Pediatr Blood Cancer 2009;52:139-142. (C) 2008 Wiley-Liss, Inc.

引用

页码：139 / 142

页数：4

共 17 条

[1] Pathogenesis of haemophagocytic lymphohistiocytosis [J].

Aricò, M ;

Danesino, C ;

Pende, D ;

Moretta, L .

BRITISH JOURNAL OF HAEMATOLOGY, 2001, 114 (04) :761-769

[2] Hematological malignancies and pregnancy:: A final report of 84 children who received chemotherapy in utero [J].

Avilés, A ;

Neri, N .

CLINICAL LYMPHOMA, 2001, 2 (03) :173-177

[3]

BASILE GD, 2001, CURR OPIN IMMUNOL, V13, P549

[4] Management of breast cancer during pregnancy using a standardized protocol [J].

Berry, DL ;

Theriault, RL ;

Holmes, FA ;

Parisi, VM ;

Booser, DJ ;

Singletary, SE ;

Buzdar, AU ;

Hortobagyi, GN .

JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (03) :855-861

[5] Macrophage activation syndrome:: characteristic findings on liver biopsy illustrating the key role of activated, IFN-γ-producing lymphocytes and IL-6- and TNF-α-producing macrophages [J].

Billiau, AD ;

Roskams, T ;

Van Damme-Lombaerts, R ;

Matthys, P ;

Wouters, C .

BLOOD, 2005, 105 (04) :1648-1651

[6] Improved outcome in haemophagocytic lymphohistiocytosis after bone marrow transplantation from related and unrelated donors:: a single-centre experience of 12 patients [J].

Dürken, M ;

Horstmann, M ;

Bieling, P ;

Erttmann, R ;

Kabisch, H ;

Löliger, C ;

Schneider, EM ;

Hellwege, HH ;

Krüger, W ;

Kröger, N .

BRITISH JOURNAL OF HAEMATOLOGY, 1999, 106 (04) :1052-1058

[7] ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR ERYTHROPHAGOCYTIC LYMPHOHISTIOCYTOSIS [J].

FISCHER, A ;

CERFBENSUSSAN, N ;

BLANCHE, S ;

LEDEIST, F ;

BREMARDOURY, C ;

LEVERGER, G ;

SCHAISON, G ;

DURANDY, A ;

GRISCELLI, C .

JOURNAL OF PEDIATRICS, 1986, 108 (02) :267-270

[8]

GIACALONE PL, 1999, CANCER, V86, P226

[9]

GWYN K, 2001, P AN M AM SOC CLIN, V20, P18

[10]

Gwyn Karin, 2005, J Natl Cancer Inst Monogr, P69

← 1 2 →