Transition Metal Photoredox Catalysis of Radical Thiol-Ene Reactions

被引：230
|
作者：
Tyson, Elizabeth L. [1 ]
Ament, Michael S. [1 ]
Yoon, Tehshik P. [1 ]
机构：
[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 78卷 / 05期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
VISIBLE-LIGHT PHOTOCATALYSIS; C-H FUNCTIONALIZATION; ELECTRON-TRANSFER; 2+2 CYCLOADDITIONS; CHEMISTRY; EFFICIENT; BOND; SELECTIVITY; OXIDATION; ALDEHYDES;
D O I：
10.1021/jo3020825
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We describe the anti-Markovnikov hydrothiolation of olefins using visible-light-absorbing transition metal photocatalysts. The key thiyl radical intermediates are generated upon quenching of photoexcited Ru*(bpz)(3)(2) with a variety of thiols. The adducts of a wide variety of olefins and thiols are formed in excellent yield (73-99%).
引用
收藏
页码：2046 / 2050
页数：5
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