Drug-induced Linear IgA Bullous Dermatosis: A Case Report and Review of the Literature

被引：71

作者：

Lammer, Judith ^{[1
]}

Hein, Ruediger ^{[1
]}

Roenneberg, Sophie ^{[1
]}

Biedermann, Tilo ^{[1
]}

Volz, Thomas ^{[1
]}

机构：

[1] Tech Univ Munich, Dept Dermatol & Allergol, Biedersteiner Str 29, DE-80802 Munich, Germany

来源：

ACTA DERMATO-VENEREOLOGICA | 2019年 / 99卷 / 06期

关键词：

drug-induced linear IgA bullous dermatosis; vancomycin; autoimmunity; EPIDERMAL NECROLYSIS; MORBILLIFORM VARIANT; BASEMENT-MEMBRANE; VANCOMYCIN; DISEASE; PATIENT; ANTIBODIES; CHILDHOOD; ASSOCIATION; DEPOSITION;

D O I：

10.2340/00015555-3154

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Linear IgA bullous dermatosis (LABD) is a rare subepidermal autoimmune blistering disease characterized by linear deposition of IgA along the basement membrane zone. Although most reported cases are idiopathic, there is a subset of patients with drug-induced LABD. Various drugs have been associated with the drug-induced form of the disease. This paper reviews the literature on drugs reported to elicit linear IgA dermatosis and its specific clinical presentation. In addition, a case report of a 77-year-old male patient with linear IgA dermatosis induced by vancomycin is described. The aim of this paper is to emphasize the need to include this differential diagnosis in cases of suspected adverse drug reactions, as well as to highlight the role of drugs in LABD.

引用

页码：508 / 515

页数：8

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