Subgenomic RNAs:: The possible building blocks for modular recombination of Closteroviridae genomes

被引:22
作者
Bar-Joseph, M [1 ]
Yang, G [1 ]
Gafny, R [1 ]
Mawassi, M [1 ]
机构
[1] Agr Res Org, S Tolkowsky Lab, Volcani Ctr, Dept Virol, IL-50250 Bet Dagan, Israel
来源
SEMINARS IN VIROLOGY | 1997年 / 8卷 / 02期
关键词
citrus tristeza virus; RNA recombination; defective RNA; RNA evolution; closteroviruses;
D O I
10.1006/smvy.1997.0116
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The Closteroviridae include several plant viruses of considerable economic importance, with unusually large positive-strand genomes of up to 20 kb. Molecular characterization of several of these viruses has now confirmed their coherent and unique position among the elongated plant RNA viruses. Structural comparisons of their genomes suggested a modular composition. The recent finding of multiple species of citrus tristeza virus (CTV) defective-RNAs, which have apparently resulted from the recombination of a subgenomic (sg)RNA, with distant parts from the 5' end of the CTV genome, suggests that Closteroviridae are probably able to utilize sgRNAs and/or their promoter signals as factors for the modular exchange and rearrangement of their genomes. (C) 1997 Academic Press.
引用
收藏
页码:113 / 119
页数:7
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