Bone mineral density in Indian women with rheumatoid arthritis

被引：20

作者：

Shankar, Subramanian ^{[1
]}

Handa, Rohini ^{[1
]}

Aneja, Ritu ^{[1
]}

Marwaha, Vishal ^{[1
]}

Ammini, A. C. ^{[1
]}

Aprajita, V. ^{[1
]}

机构：

[1] All India Inst Med Sci, New Delhi, India

来源：

RHEUMATOLOGY INTERNATIONAL | 2009年 / 29卷 / 04期

关键词：

Rheumatoid arthritis; Osteoporosis; Osteopenia; BMD; Modified Sharp score; Asian Indian; VITAMIN-D; OSTEOPOROSIS; PREVALENCE; REGISTER;

D O I：

10.1007/s00296-008-0706-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Osteoporosis (OP) is being increasingly recognized in inflammatory rheumatic diseases like rheumatoid arthritis (RA). Ethnicity influences bone mineral density (BMD) and fracture risk. Due to paucity of data on this aspect of RA from Asian countries including India, we prospectively studied 84 premenopausal women with RA of at least 2 years duration and 247 healthy, age (within 5 years) and sex-matched controls. A significant difference in BMD between patients and controls was observed only at the femoral neck. As many as 22% patients with RA exhibited osteoporosis at least one site in contrast to 9% controls. Nearly 40% of patients exhibited osteopenia at all the three sites. Modified Sharp score, disease duration and DMARD naive period were found to correlate with low BMD. However, on multivariate analysis, only modified Sharp score was shown to be significantly associated with low BMD. Our study draws attention to the poor bone health in Asian Indian women with RA.

引用

页码：377 / 381

页数：5

共 19 条

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