New antimycobacterial S-alkyllsothiosemicarbazones

被引:7
作者
Waisser, K [1 ]
Heinisch, L
Slosárek, M
Janota, J
机构
[1] Charles Univ, Fac Pharm, Dept Inorgan & Organ Chem, Hradec Kralove 50005, Czech Republic
[2] Hans Knoll Inst, D-07745 Jena, Germany
[3] Natl Inst Publ Hlth, Prague, Czech Republic
关键词
D O I
10.1007/BF02931433
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
In connection with a systematic study of antimycobacterial agents against potentially pathogenic strains the series of 12 S-alkylisothiosemicarbazones was evaluated for in vitro antimycobacterial activity against Mycobacterium tuberculosis, M. kansasii, M fortuitum, two strains of M. intracellulare and three strains of M avium. Quinoline-4-carbaldehyde-S-hexyl-isothiohydrazone was found to be more active against potentially pathogenic strains than isoniazide.
引用
收藏
页码:479 / 481
页数:3
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