Up in Smoke? A Preliminary Open-Label Trial of Nicotine Replacement Therapy and Cognitive Behavioral Motivational Enhancement for Smoking Cessation Among Youth in Los Angeles

被引：4

作者：

Swanson, Aimee-Noelle ^{[1
]}

Shoptaw, Steven ^{[2
]}

Heinzerling, Keith Gregory ^{[1
]}

Wade, Adam C. ^{[1
]}

Worley, Matthew ^{[3
]}

McCracken, James ^{[2
]}

Wilson, Sarah A. ^{[4
]}

Asarnow, Joan ^{[2
]}

London, Edythe D. ^{[2
,5
]}

机构：

[1] UCLA, David Geffen Sch Med, Dept Family Med, Los Angeles, CA 90024 USA

[2] UCLA, David Geffen Sch Med, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90024 USA

[3] Univ Calif San Diego, San Diego State Univ, San Diego Joint Doctoral Program Clin Psychol, San Diego, CA 92103 USA

[4] Univ Calif Los Angeles, Semel Inst Neurosci & Human Behav, Los Angeles, CA USA

[5] UCLA, David Geffen Sch Med, Dept Mol & Med Pharmacol, Los Angeles, CA 90024 USA

来源：

SUBSTANCE USE & MISUSE | 2013年 / 48卷 / 14期

关键词：

smoking cessation; adolescents; youth; tobacco; nicotine; ADOLESCENT SMOKERS; DOUBLE-BLIND; BUPROPION; VARENICLINE; DEPRESSION; DEPENDENCE; SYMPTOMS; EFFICACY; PATTERNS;

D O I：

10.3109/10826084.2013.808218

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

In 2008-2009, we conducted a 6-week, open-label trial of transdermal nicotine replacement therapy and practical counseling for 34 adolescents seeking smoking cessation in Los Angeles. Dependent outcomes were study retention, use of the patch, and 7-day quit status at the end-of-study and at follow-up visits. Predictors of outcomes included cigarette dependence, withdrawal symptoms, demographic and psychiatric measures, and other substance use. Variables significant in bivariate analysis (p < .10) were retained in a multi-variate model. Subjects had significant pre-to-post reductions in quit rates, dependence, and withdrawal symptoms. Subjects also reported a high number of co-morbidities. Implications for clinicians are discussed.

引用

页码：1553 / 1562

页数：10

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