Progress towards elimination goals for viral hepatitis

被引：152

作者：

Cox, Andrea L. ^{[1
]}

El-Sayed, Manal H. ^{[2
]}

Kao, Jia-Horng ^{[3
,4
]}

Lazarus, Jeffrey V. ^{[5
]}

Lemoine, Maud ^{[6
]}

Lok, Anna S. ^{[7
]}

Zoulim, Fabien ^{[8
,9
,10
]}

机构：

[1] Johns Hopkins Univ, Dept Med, Baltimore, MD 21218 USA

[2] Ain Shams Univ, Dept Paediat, Cairo, Egypt

[3] Natl Taiwan Univ Hosp, Div Gastroenterol & Hepatol, Dept Internal Med, Taipei, Taiwan

[4] Natl Taiwan Univ, Grad Inst Clin Med, Coll Med, Taipei, Taiwan

[5] Univ Barcelona, Barcelona Inst Global Hlth ISGlobal, Hosp Clin, Barcelona, Spain

[6] Imperial Coll London, St Marys Hosp, Dept Metab Digest & Reprod, Div Digest Dis,Hepatol Sect, London, England

[7] Univ Michigan, Dept Internal Med, Div Gastroenterol & Hepatol, Ann Arbor, MI 48109 USA

[8] Lyon Univ, Med Sch, Lyon, France

[9] Hosp Civils Lyon, Hepatol Dept, Lyon, France

[10] INSERM, CRCL, U1052, Viral Hepatitis Res Lab, Lyon, France

来源：

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY | 2020年 / 17卷 / 09期

关键词：

B-VIRUS INFECTION; C-VIRUS; GLOBAL ELIMINATION; CHALLENGES; DISEASE; TAIWAN;

D O I：

10.1038/s41575-020-0332-6

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The global burden of viral hepatitis is substantial; in terms of mortality, hepatitis B virus and hepatitis C virus infections are on a par with HIV, malaria and tuberculosis, among the top four global infectious diseases. In 2016, the 194 Member States of the World Health Organization committed to eliminating viral hepatitis as a public health threat by 2030, with a particular focus on hepatitis B virus and hepatitis C virus infection. With only 10 years to go until the 2030 deadline is reached, and although much progress has been made towards elimination, there are still some important gaps in terms of policy and progress. In this Viewpoint, we asked a selection of scientists and clinicians working in the viral hepatitis field for their opinions on whether elimination of viral hepatitis by 2030 is feasible, what the key areas of progress are and what the focus for the next 10 years and beyond should be for viral hepatitis elimination.

引用

页码：533 / 542

页数：10

共 66 条

[1]

[Anonymous], 2013, Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach

[2] Progress and challenges of a pioneering hepatitis C elimination program in the country of Georgia [J].

Averhoff, Francisco ;

Shadaker, Shaun ;

Gamkrelidze, Amiran ;

Kuchuloria, Tatia ;

Gvinjilia, Lia ;

Getia, Vladimer ;

Sergeenko, David ;

Butsashvili, Maia ;

Tsertsvadze, Tengiz ;

Sharvadze, Lali ;

Zarkua, Jaba ;

Skaggs, Beth ;

Nasrullah, Muazzam .

JOURNAL OF HEPATOLOGY, 2020, 72 (04) :680-687

[3] Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies [J].

Bartenschlager, Ralf ;

Baumert, Thomas F. ;

Bukh, Jens ;

Houghton, Michael ;

Lemon, Stanley M. ;

Lindenbach, Brett D. ;

Lohmann, Volker ;

Moradpour, Darius ;

Pietschmann, Thomas ;

Rice, Charles M. ;

Thimme, Robert ;

Wakita, Takaji .

VIRUS RESEARCH, 2018, 248 :53-62

[4] Impact of DAAs on liver transplantation: Major effects on the evolution of indications and results. An ELITA study based on the ELTR registry [J].

Belli, Luca Saverio ;

Perricone, Giovanni ;

Adam, Rene ;

Cortesi, Paolo A. ;

Strazzabosco, Mario ;

Facchetti, Rita ;

Karam, Vincent ;

Salizzoni, Mauro ;

Andujar, Rafael Lopez ;

Fondevila, Costantino ;

De Simone, Paolo ;

Morelli, Cristina ;

Fabregat-Prous, Joan ;

Samuel, Didier ;

Agarwaal, Kosh ;

Gonzales, Enrique Moreno ;

Charco, Ramon ;

Zieniewicz, Krzysztof ;

De Carlis, Luciano ;

Duvoux, Christophe .

JOURNAL OF HEPATOLOGY, 2018, 69 (04) :810-817

[5] The epidemiology of hepatitis delta virus infection in Cameroon [J].

Besombes, Camille ;

Njouom, Richard ;

Paireau, Juliette ;

Lachenal, Guillaume ;

Texier, Gaetan ;

Tejiokem, Mathurin ;

Cauchemez, Simon ;

Pepin, Jacques ;

Fontanet, Arnaud .

GUT, 2020, 69 (07) :1294-1300

[6] Taiwan commits to eliminating hepatitis C in 2025 [J].

Chen, Ding-Shinn .

LANCET INFECTIOUS DISEASES, 2019, 19 (05) :466-467

[7] Fighting Against Viral Hepatitis: Lessons from Taiwan [J].

Chen, Ding-Shinn .

HEPATOLOGY, 2011, 54 (02) :381-392

[8]

Coalition for Global Hepatitis Elimination, 2019, HEP PREV CONTR EL MO

[9] Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission [J].

Cooke, Graham S. ;

Andrieux-Meyer, Isabelle ;

Applegate, Tanya L. ;

Atun, Rifat ;

Burry, Jessica R. ;

Cheinquer, Hugo ;

Dusheiko, Geoff ;

Feld, Jordan J. ;

Gore, Charles ;

Griswold, Max G. ;

Hamid, Saeed ;

Hellard, Margaret E. ;

Hou, JinLin ;

Howell, Jess ;

Jia, Jidong ;

Kravchenko, Natalia ;

Lazarus, Jeffrey V. ;

Lemoine, Maud ;

Lesi, Olufunmilayo A. ;

Maistat, Liudmyla ;

McMahon, Brian J. ;

Razavi, Homie ;

Roberts, Teri R. ;

Simmons, Bryony ;

Sonderup, Mark W. ;

Spearman, C. Wendy ;

Taylor, Bridie E. ;

Thomas, David L. ;

Waked, Imam ;

Ward, John W. ;

Wiktor, Stefan Z. ;

Abdo, Ayman ;

Aggarwal, Rakesh ;

Aghemo, Alessio ;

Al-Judaibi, Bandar ;

Al Mahtab, Mamun ;

Altaf, Arshad ;

Ameen, Zyaad ;

Asselah, Tarik ;

Baatarkkhuu, Oidov ;

Barber, Ella ;

Barnes, Eleanor ;

Boulet, Pascale ;

Burrows, Louise ;

Butsashvili, Maia ;

Chan, Erica ;

Chow, Chelsea ;

Cowie, Ben ;

Cunningham, Chris ;

de Araujo, Alexandre .

LANCET GASTROENTEROLOGY & HEPATOLOGY, 2019, 4 (02) :135-184

[10]

Cornberg M, 2020, HEPATOLOGY, V71, P1070, DOI [10.1002/hep.31030, 10.1016/j.jhep.2019.11.003]

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