Abnormal spiral arteries modification in stillbirths: the role of maternal prepregnancy body mass index

被引：18

作者：

Avagliano, Laura ^{[1
]}

Marconi, Anna Maria ^{[1
]}

Romagnoli, Solange ^{[2
]}

Bulfamante, Gaetano Pietro ^{[2
]}

机构：

[1] Univ Milan, Dept Obstet & Gynecol, DMSD San Paolo, San Paolo Hosp,Med Sch, I-20142 Milan, Italy

[2] Univ Milan, Dept Human Pathol, DMSD San Paolo, San Paolo Hosp,Med Sch, I-20142 Milan, Italy

来源：

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2012年 / 25卷 / 12期

关键词：

Fetal death; obesity; histological evaluation; placenta; pregnancy outcome; RISK-FACTORS; COUNTRIES; RATES;

D O I：

10.3109/14767058.2012.705395

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Aim: To evaluate the prevalence of abnormal spiral arteries modification (ASAM) in stillbirths and its anatomo-clinical correlations. Methods: Two-hundred and three placentas of stillbirth >= 20 weeks of gestation were analyzed. Results: ASAM was present in 69/203 cases (33.9%). The only maternal characteristic that significantly differed in ASAM versus normal spiral arteries modification (NSAM) cases was the prepregnancy body mass index (BMI) (25.9 +/- 6.1 and 23.1 +/- 4.2 kg/m(2), respectively) with 15.9% of obesity in ASAM mothers versus 5.2% in NSAM (p = 0.02). Conclusion: Given the association between obesity and adverse pregnancy outcome, our data suggest that counselling obese women to lose weight before pregnancy becomes increasingly imperative.

引用

收藏

页码：2789 / 2792

页数：4

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