Antibacterial activity of crude methanolic extract and its fractions of aerial parts of Anthemis tinctoria

被引:0
|
作者
Akgul, C [1 ]
Saglikoglu, G [1 ]
机构
[1] Canakkale Onsekiz Mart Univ, Fac Arts & Sci, Dept Chem, TR-17100 Canakkale, Turkey
来源
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS | 2005年 / 42卷 / 06期
关键词
Anthemis tinctoria; antibacterial activity; Pseudomonas aeruginosa; Staphylococcus aureus; MIC; MBC;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The antibacterial activity of the methanolic extract and its fractions of aerial parts of Awheinis tinctoria (Asteraceae) was investigated against representative gram-positive Staphylococcus aureus (ATCC 25923) and Enterococcus faecalis (ATCC 29212) and gram-negative strains Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853). The activity was concentrated mainly in the dichloromethane (DCM) and hexane fractions of crude methanolic extract. The 5 mg of DCM extract per disk produced 15-16 mm of inhibition zone against S. aureus and P. aeruginosa, however. no activity was found against E. faecalis and E. coli. The hexane fraction showed activity against S. aureus. P. aeruginosa and E. faecalis. As DCM fraction showed the highest antibacterial activity in the disk diffusion assay, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of only this fraction was determined against S. aureus and P. aeruginosa. These values were found to be in the range of 1.25 to 10 mg/ml.
引用
收藏
页码:395 / 397
页数:3
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