Polysubstituted pyrrole derivatives via 1,2-alkenyl migration of novel γ-amino-α,β-unsaturated aldehydes and α-diazocarbonyls

被引：6

作者：

Cai, Shuting ^{[1
]}

Zeng, Jing ^{[1
]}

Li, Yongxin ^{[1
]}

Liu, Xue-Wei ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore

来源：

RSC ADVANCES | 2014年 / 4卷 / 14期

关键词：

CATALYZED REACTIONS; ACID; REARRANGEMENTS; ACCESS; SHIFT;

D O I：

10.1039/c3ra47020b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Tri-substituted pyrrole derivatives were successfully synthesized from aminoaldehyde and alpha-diazocarbonyl, using a TiCl4 catalyst. The reactions proceeded via 1,2-migration and condensation, leading to the corresponding pyrroles in moderate to excellent yields. Reaction susceptibility was subsequently demonstrated by the variation in substrates.

引用

页码：7275 / 7278

页数：4

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