A High-Yielding Biocatalytic Process for the Production of 2-O-(α-D-glucopyranosyl)-sn-glycerol, a Natural Osmolyte and Useful Moisturizing Ingredient

被引：103

作者：

Goedl, Christiane ^{[1
]}

Sawangwan, Thornthan ^{[1
]}

Mueller, Mario ^{[1
]}

Schwarz, Alexandra ^{[1
]}

Nidetzky, Bernd ^{[1
]}

机构：

[1] Graz Univ Technol, Inst Biotechnol & Biochem Engn, A-8010 Graz, Austria

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 52期

基金：

奥地利科学基金会;

关键词：

enzymatic synthesis; glycosides; kinetics; regioselectivity; transglucosylation;

D O I：

10.1002/anie.200803562

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Fit for industry: Stereochemically pure 2-O-(α-D-glucopyranosyl)-sn-glycerol (αGG) was obtained in high yield from an efficient and selective biocatalytic process (see schematic outline). The sucrose phosphorylase catalyzed transfer of a glucosyl group from sucrose to glycerol unites the main advantages of transglycosidases, glycosyltransferases, and glycosynthases for glycoside synthesis and provides access to αGG as an industrial chemical. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：10086 / 10089

页数：4

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