Membrane phospholipid asymmetry: Host response to the externalization of phosphatidylserine

被引：26
|
作者：
Bruckheimer, EM [1 ]
Schroit, AJ [1 ]
机构：
[1] UNIV TEXAS,MD ANDERSON CANC CTR,DEPT CELL BIOL,HOUSTON,TX 77030
来源：
JOURNAL OF LEUKOCYTE BIOLOGY | 1996年 / 59卷 / 06期
关键词：
lipid asymmetry; erythrocytes; macrophages;
D O I：
10.1002/jlb.59.6.784
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Membrane phospholipid asymmetry is an important regulator of cellular function and homeostasis. The activities of lipid transporters are contributing factors to the regulation of membrane lipid composition over the Lifespan of the cell. Alterations in the activites of these proteins result in the movement of phosphatidylserine to the cell's outer leaflet, This promotes several physiologic responses including initiation of the coagulation cascade and cell recognition by the reticuloendothelial system.
引用
收藏
页码：784 / 788
页数：5
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