Sensing conformational changes in metabotropic glutamate receptors

被引：1

作者：

Rives, Marie-Laure ^{[1
,3
]}

Javitch, Jonathan A. ^{[1
,2
,3
]}

机构：

[1] Columbia Univ Coll Phys & Surg, Dept Psychiat, New York, NY 10032 USA

[2] Columbia Univ Coll Phys & Surg, Dept Pharmacol, New York, NY 10032 USA

[3] New York State Psychiat Inst & Hosp, Div Mol Therapeut, New York, NY 10032 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2013年 / 110卷 / 15期

关键词：

ACTIVATION; MECHANISMS;

D O I：

10.1073/pnas.1303736110

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：5742 / 5743

页数：2

共 17 条

[1] Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement [J].

Brock, Carsten ;

Oueslati, Nadia ;

Soler, Stephan ;

Boudier, Laure ;

Rondard, Philippe ;

Pin, Jean-Philippe .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (45) :33000-33008

[2]

Dobrovetsky E, STRUCTURAL GENOMICS, DOI [10.2210/pdb3lmk/pdb, DOI 10.2210/PDB31MK/PDB]

[3]

Doumazane E, 2013, P NATL ACAD SCI USA, V110, pE1416, DOI 10.1073/pnas.1215615110

[4] Ligand Bias at Metabotropic Glutamate 1a Receptors: Molecular Determinants That Distinguish β-Arrestin-Mediated from G Protein-Mediated Signaling [J].

Emery, Andrew C. ;

DiRaddo, John O. ;

Miller, Eric ;

Hathaway, Hannah A. ;

Pshenichkin, Sergey ;

Takoudjou, Guy Rodrigue ;

Grajkowska, Ewa ;

Yasuda, Robert P. ;

Wolfe, Barry B. ;

Wroblewski, Jarda T. .

MOLECULAR PHARMACOLOGY, 2012, 82 (02) :291-301

[5] Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor [J].

Kunishima, N ;

Shimada, Y ;

Tsuji, Y ;

Sato, T ;

Yamamoto, M ;

Kumasaka, T ;

Nakanishi, S ;

Jingami, H ;

Morikawa, K .

NATURE, 2000, 407 (6807) :971-977

[6] Ligand functional selectivity advances our understanding of drug mechanisms and drug discovery [J].

Mailman, Richard B. ;

Murthy, Vishakantha .

NEUROPSYCHOPHARMACOLOGY, 2010, 35 (01) :345-346

[7] Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization [J].

Maurel, Damien ;

Comps-Agrar, Laetitia ;

Brock, Carsten ;

Rives, Marie-Laure ;

Bourrier, Emmanuel ;

Ayoub, Mohammed Akli ;

Bazin, Herve ;

Tinel, Norbert ;

Durroux, Thierry ;

Prezeau, Laurent ;

Trinquet, Eric ;

Pin, Jean-Philippe .

NATURE METHODS, 2008, 5 (06) :561-567

[8] Structures of the extracellular regions of the group II/III metabotropic glutamate receptors [J].

Muto, Takanori ;

Tsuchiya, Daisuke ;

Morikawa, Kosuke ;

Jingami, Hisato .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (10) :3759-3764

[9] Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease [J].

Niswender, Colleen M. ;

Conn, P. Jeffrey .

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2010, 50 :295-322

[10] The Dynamic Process of β2-Adrenergic Receptor Activation [J].

Nygaard, Rie ;

Zou, Yaozhong ;

Dror, Ron O. ;

Mildorf, Thomas J. ;

Arlow, Daniel H. ;

Manglik, Aashish ;

Pan, Albert C. ;

Liu, Corey W. ;

Fung, Juan Jose ;

Bokoch, Michael P. ;

Thian, Foon Sun ;

Kobilka, Tong Sun ;

Shaw, David E. ;

Mueller, Luciano ;

Prosser, R. Scott ;

Kobilka, Brian K. .

CELL, 2013, 152 (03) :532-542

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