Effects of cadmium exposure on antioxidant enzymes and histological changes in the mud shrimp Austinogebia edulis (Crustacea: Decapoda)

被引：67

作者：

Das, Shagnika ^{[1
,2
]}

Tseng, Li-Chun ^{[1
]}

Chou, Chi ^{[3
]}

Wang, Lan ^{[4
]}

Souissi, Sami ^{[2
]}

Hwang, Jiang-Shiou ^{[1
,5
]}

机构：

[1] Natl Taiwan Ocean Univ, Inst Marine Biol, Keelung, Taiwan

[2] Univ Littoral Cote dOpale, Univ Lille, CNRS, LOG,UMR 8187, F-62930 Wimereux, France

[3] Mackay Mem Hosp, Dept Pathol, New Taipei 25160, Taiwan

[4] Shanxi Univ, Sch Life Sci, Taiyuan, Shanxi, Peoples R China

[5] Natl Taiwan Ocean Univ, Ctr Excellence Oceans, Keelung, Taiwan

来源：

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH | 2019年 / 26卷 / 08期

关键词：

Oxidative damage; Cadmium; Antioxidant enzyme; Mud shrimp; Austinogebia edulis; Hepatopancreas; Gill; Muscle; OXIDATIVE STRESS; LIPID-PEROXIDATION; HEAVY-METALS; ULTRASTRUCTURAL ALTERATIONS; ERIOCHEIR-SINENSIS; WHITE SHRIMP; TRACE-METALS; DNA-DAMAGE; HEPATOPANCREAS; CATALASE;

D O I：

10.1007/s11356-018-04113-x

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The trace metal cadmium (Cd) is a toxic pollutant known to induce oxidative stress and other sublethal to lethal effects on aquatic organisms. We exposed the marine mud shrimp Austinogebia edulis to Cd concentrations of 0, 0.5, and 5mg/kg for up to 4days (24, 48, 72, 96h). We studied the activity of antioxidant enzymes in the hepatopancreas, gill, and muscle of A. edulis. Antioxidant enzymes (SOD, CAT, and GPx) decreased with increasing Cd concentration and extended exposure time in these three organs of the mud shrimp A. edulis. Increasing Cd concentration led to an increase in ROS and resulted ultimately in membrane lipid peroxidation at higher Cd concentrations. Significant damage of the hepatopancreas of A. edulis was noticed at higher concentrations of Cd, showing damages like the disappearance of epithelial cell boundaries, detachment of cells from the basal lamina, cellular swelling, necrosis, and reduction of glycogen. In conclusion, Cd caused oxidative damage by reducing the activities of antioxidant enzymes and by damaging the tissue structure in major organs of the mud shrimp A. edulis.

引用

页码：7752 / 7762

页数：11

共 69 条

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