VCSEL optoelectronic biosensor for detection of infectious diseases

被引:22
作者
Huang, Michael C. Y. [1 ]
Mateus, Carlos F. R. [2 ]
Foley, Jonathan E. [3 ]
Beatty, Robert [4 ]
Cunningham, Brian T. [5 ]
Chang-Hasnain, Connie J. [1 ]
机构
[1] Univ Calif Berkeley, Dept Elect Engn & Comp Sci, Berkeley, CA 94720 USA
[2] Inst Estudos Avancados, BR-12228 Sao Jose Dos Campos, Brazil
[3] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA
[4] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
[5] Univ Illinois, Dept Elect & Comp Engn, Urbana, IL 61801 USA
关键词
biomedical transducer; medical diagnosis; vertical-cavity surface-emitting lasers (VCSELs);
D O I
10.1109/LPT.2008.916947
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We report on the detection of human anti-dengue antibodies from serum samples using a compact optoelectronic label-free biosensor. The system consists of a tunable vertical-cavity surface-emitting laser, guided-mode resonant sensor surface, and two silicon pin detectors. This novel biosensor demonstrated sufficient sensitivity in a clinical-relevant assay, making it a potential new platform for simplified and rapid point-of-care diagnostic tests for the detection of infectious diseases.
引用
收藏
页码:443 / 445
页数:3
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