The unique tryptophan residue of the vitamin D receptor is critical for ligand binding and transcriptional activation.

被引:0
|
作者
Solomon, CR
Macoritto, M
Gao, XL
White, JH
Kremer, R
机构
[1] McGill Univ, Dept Med, Montreal, PQ, Canada
[2] McGill Univ, Dept Chem, Montreal, PQ, Canada
[3] McGill Univ, Dept Physiol, Montreal, PQ, Canada
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
T458
引用
收藏
页码:S213 / S213
页数:1
相关论文
共 50 条
  • [1] The unique tryptophan residue of the vitamin D receptor is critical for ligand binding and transcriptional activation
    Solomon, C
    Macoritto, M
    Gao, XL
    White, JH
    Kremer, R
    JOURNAL OF BONE AND MINERAL RESEARCH, 2001, 16 (01) : 39 - 45
  • [2] Tryptophan 299 is a conserved residue of human pregnane X receptor critical for the functional consequence of ligand binding
    Banerjee, Monimoy
    Chai, Sergio C.
    Wu, Jing
    Robbins, Delira
    Chen, Taosheng
    BIOCHEMICAL PHARMACOLOGY, 2016, 104 : 131 - 138
  • [3] The vitamin D receptor - Structure and transcriptional activation
    Strugnell, SA
    DeLuca, HF
    PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1997, 215 (03): : 223 - 228
  • [4] LIGAND OCCUPANCY IS NOT REQUIRED FOR VITAMIN-D-RECEPTOR AND RETINOID RECEPTOR-MEDIATED TRANSCRIPTIONAL ACTIVATION
    MATKOVITS, T
    CHRISTAKOS, S
    MOLECULAR ENDOCRINOLOGY, 1995, 9 (02) : 232 - 242
  • [5] Characterization of transcriptional activation and DNA-binding functions in the hinge region of the vitamin D receptor
    Shaffer, PL
    McDonnell, DP
    Gewirth, DT
    BIOCHEMISTRY, 2005, 44 (07) : 2678 - 2685
  • [6] LIGAND OCCUPANCY IS NOT REQUIRED FOR VITAMIN-D RECEPTOR AND RETINOID-X RECEPTOR-MEDIATED TRANSCRIPTIONAL ACTIVATION
    MATKOVITS, T
    CHRISTAKOS, S
    JOURNAL OF BONE AND MINERAL RESEARCH, 1993, 8 : S139 - S139
  • [7] Mediating transcriptional activation by the vitamin D3 receptor
    Freedman, LP
    Rachez, C
    Burakov, D
    Gamble, MJ
    Yang, W
    Chang, CP
    BONE, 2001, 28 (05) : S69 - S69
  • [8] Transcriptional activation and dimerization functions in the human vitamin D receptor
    Jin, CH
    Kerner, SA
    Hong, MH
    Pike, JW
    MOLECULAR ENDOCRINOLOGY, 1996, 10 (08) : 945 - 957
  • [9] The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation
    El Kharraz, Sarah
    Dubois, Vanessa
    van Royen, Martin E.
    Houtsmuller, Adriaan B.
    Pavlova, Ekatarina
    Atanassova, Nina
    Tien Nguyen
    Voet, Arnout
    Eerlings, Roy
    Handle, Florian
    Prekovic, Stefan
    Smeets, Elien
    Moris, Lisa
    Devlies, Wout
    Ohlsson, Claes
    Poutanen, Matti
    Verstrepen, Kevin J.
    Carmeliet, Geert
    Launonen, Kaisa-Mari
    Helminen, Laura
    Palvimo, Jorma J.
    Libert, Claude
    Vanderschueren, Dirk
    Helsen, Christine
    Claessens, Frank
    EMBO REPORTS, 2021, 22 (12)
  • [10] Characterization of unique DNA-binding and transcriptional-activation functions in the carboxyl-terminal extension of the zinc finger region in the human vitamin D receptor
    Hsieh, JC
    Whitfield, GK
    Oza, AK
    Dang, HTL
    Price, JN
    Galligan, MA
    Jurutka, PW
    Thompson, PD
    Haussler, CA
    Haussler, MR
    BIOCHEMISTRY, 1999, 38 (49) : 16347 - 16358