Bisnorditerpene, Norditerpene, and Lipo-alkaloids from Aconitum toxicum

被引:20
作者
Csupor, Dezso [1 ]
Forgo, Peter [1 ]
Wenzig, Eva Maria [2 ]
Bauer, Rudolf [2 ]
Hohmann, Judit [1 ]
机构
[1] Univ Szeged, Dept Pharmacognosy, H-6720 Szeged, Hungary
[2] Karl Franzens Univ Graz, Dept Pharmacognosy, Inst Pharmaceut Sci, A-8010 Graz, Austria
来源
JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 10期
关键词
D O I
10.1021/np800322q
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
From the roots of Aconitum toxicum, acotoxicine (1), a new bisnorditerpene alkaloid, was isolated together with the structurally related delavaconitine, delavaconine, dolaconine, aconosine, and the norditerpene alkaloid neolinine. The structure of compound 1 was elucidated by spectroscopic data interpretation. Further, eight lipo-alkaloids (2-9) were detected in the plant material by LC-APCI-MSn analysis. This is the first report of a C-18 bisnorditerpene alkaloid and lipo-alkaloids from A. toxicum.
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页码:1779 / 1782
页数:4
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