Relative adrenal failure in the ICU: An identifiable problem requiring treatment

被引：28
作者：
Gonzalez, H [1 ]
Nardi, O [1 ]
Annane, D [1 ]
机构：
[1] Hop Raymond Poincare, Serv Reanimat Med, F-92380 Garches, France
来源：
CRITICAL CARE CLINICS | 2006年 / 22卷 / 01期
关键词：
D O I：
10.1016/j.ccc.2005.09.001
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Critically ill patients at some stage may develop adrenal insufficiency (AI). This article reviews the mechanisms, diagnosis criteria, consequences, and treatment of AI in various ICU conditions. Glucocorticoid insufficiency may be related to a decrease in glucocorticoid synthesis (ie, adrenal insufficiency) or to a reduced delivery of glucocorticoid to target tissues and cells. Diagnosis relies on clinical suspicion and ACTH test results. The length of cortisol replacement therapy should be at least 7 days and the adjunction of fludrocortisone is recommended.
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页码：105 / +
页数：15
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