Diagnosis and management of acute graft-versus-host disease

被引:258
作者
Dignan, Fiona L. [1 ,2 ]
Clark, Andrew
Amrolia, Persis
Cornish, Jacqueline
Jackson, Graham
Mahendra, Prem
Scarisbrick, Julia J.
Taylor, Peter C.
Hadzic, Nedim
Shaw, Bronwen E. [1 ]
Potter, Michael N. [1 ]
机构
[1] Royal Marsden NHS Fdn Trust, Sect Haematooncol, London, England
[2] St Thomas Hosp, St Johns Inst Dermatol, London, England
关键词
acute graft-versus-host disease; aGvHD; transplant; management; diagnosis; MESENCHYMAL STEM-CELLS; ORAL BECLOMETHASONE DIPROPIONATE; BONE-MARROW-TRANSPLANTATION; LOW-DOSE METHOTREXATE; REFRACTORY ACUTE; EXTRACORPOREAL PHOTOCHEMOTHERAPY; MYCOPHENOLATE-MOFETIL; STEROID-RESISTANT; ANTITHYMOCYTE GLOBULIN; HEPATIC GRAFT;
D O I
10.1111/j.1365-2141.2012.09129.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A joint working group established by the Haemato-oncology subgroup of the British Committee for Standards in Haematology (BCSH) and the British Society for Bone Marrow Transplantation (BSBMT) has reviewed the available literature and made recommendations for the diagnosis and management of acute graft-versus-host disease. This guideline includes recommendations for the diagnosis and grading of acute graft-versus-host disease as well as primary treatment and options for patients with steroid-refractory disease. The goal of treatment should be effective control of graft-versus-host disease while minimizing risk of toxicity and relapse.
引用
收藏
页码:30 / 45
页数:16
相关论文
共 138 条
[91]  
Perotti C, 1999, HAEMATOLOGICA, V84, P237
[92]   Extracorporeal photochemotherapy in graft-versus-host disease: a longitudinal study on factors influencing the response and survival in pediatric patients [J].
Perotti, Cesare ;
Del Fante, Claudia ;
Tinelli, Carmine ;
Viarengo, Gianluca ;
Scudeller, Luigia ;
Zecca, Marco ;
Locatelli, Franco ;
Salvaneschi, Laura .
TRANSFUSION, 2010, 50 (06) :1359-1369
[93]   Sirolimus demonstrates activity in the primary therapy of acute graft-versus-host disease without systemic glucocorticoids [J].
Pidala, Joseph ;
Tomblyn, Marcie ;
Nishihori, Taiga ;
Field, Teresa ;
Ayala, Ernesto ;
Perkins, Janelle ;
Fernandez, Hugo ;
Locke, Fred ;
Perez, Lia ;
Ochoa, Jose Leonel ;
Alsina, Melissa ;
Anasetti, Claudio .
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2011, 96 (09) :1351-1356
[94]  
Pidala J, 2010, ANN TRANSPL, V15, P21
[95]   Infliximab for Managing Steroid-Refractory Acute Graft-versus-Host Disease [J].
Pidala, Joseph ;
Kim, Jongphil ;
Field, Teresa ;
McBride, Ali ;
Kharfan-Dabaja, Mohamed ;
Perkins, Janelle ;
Fernandez, Hugo ;
Perez, Lia ;
Ayala, Ernesto ;
Anasetti, Claudio .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2009, 15 (09) :1116-1121
[96]   Encouraging results with inolimomab (anti-IL-2 receptor) as treatment for refractory acute graft-versus-host disease [J].
Pinana, Jose Luis ;
Valcarcel, David ;
Martino, Rodrigo ;
Moreno, M. Estela ;
Sureda, Anna ;
Briones, Javier ;
Brunet, Salut ;
Sierra, Jorge .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2006, 12 (11) :1135-1141
[97]   Multilineage potential of adult human mesenchymal stem cells [J].
Pittenger, MF ;
Mackay, AM ;
Beck, SC ;
Jaiswal, RK ;
Douglas, R ;
Mosca, JD ;
Moorman, MA ;
Simonetti, DW ;
Craig, S ;
Marshak, DR .
SCIENCE, 1999, 284 (5411) :143-147
[98]   Endoscopic and histologic diagnosis of intestinal graft-versus-host disease after marrow transplantation [J].
Ponec, RJ ;
Hackman, RC ;
McDonald, GB .
GASTROINTESTINAL ENDOSCOPY, 1999, 49 (05) :612-621
[99]   Efficacy and Safety of Ex Vivo Cultured Adult Human Mesenchymal Stem Cells (Prochymal™) in Pediatric Patients with Severe Refractory Acute Graft-Versus-Host Disease in a Compassionate Use Study [J].
Prasad, Vinod K. ;
Lucas, Kenneth G. ;
Kleiner, Gary I. ;
Talano, Julie An M. ;
Jacobsohn, David ;
Broadwater, Gloria ;
Monroy, Rod ;
Kurtzberg, Joanne .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2011, 17 (04) :534-541
[100]   Daclizumab, a humanized anti-interleukin-2 receptor alpha chain antibody, for treatment of acute graft-versus-host disease [J].
Przepiorka, D ;
Kernan, NA ;
Ippoliti, C ;
Papadopoulos, EB ;
Giralt, S ;
Khouri, I ;
Lu, JG ;
Gajewski, J ;
Durett, A ;
Cleary, K ;
Champlin, R ;
Andersson, BS ;
Light, S .
BLOOD, 2000, 95 (01) :83-89