The Interaction of HIV With Mental Health in the Modern Antiretroviral Therapy Era

被引:3
|
作者
Carrico, Adam W. [1 ]
Rubin, Leah H. [2 ,3 ,4 ]
Paul, Robert H. [5 ]
机构
[1] Univ Miami, Miller Sch Med, Dept Publ Hlth Sci, 1120NW 14th St,Off 1005, Miami, FL 33136 USA
[2] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA
[3] Johns Hopkins Univ, Sch Med, Dept Psychiat & Behav Sci, Baltimore, MD 21205 USA
[4] Johns Hopkins Univ, Dept Epidemiol, Bloomberg Sch Publ Hlth, Baltimore, MD USA
[5] Univ Missouri, Dept Psychol Sci, St Louis, MO 63121 USA
来源
PSYCHOSOMATIC MEDICINE | 2022年 / 84卷 / 08期
关键词
depression; HIV; mental health; methamphetamine; microbiome; psychoneuroimmunology; AIDS = acquired immune deficiency syndrome; ART = antiretroviral therapy; HAART = highly active anti-retroviral therapy; HIV = human immunodeficiency virus; PWH = people with HIV; SIV = simian immunodeficiency virus; PSYCHOSOCIAL STRESS; VIRAL LOAD; DEPRESSION; ACTIVATION; INFLAMMATION; PROGRESSION; OUTCOMES; STIGMA;
D O I
10.1097/PSY.0000000000001134
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
People with HIV (PWH) receiving effective antiretroviral therapy (ART) continue to display residual immune dysregulation that amplifies the risk for neuropsychiatric comorbidities. At the same time, PWH commonly experience intersectional stigma and other psychosocial stressors that are linked to neuroendocrine stress responses, potentiate residual immune dysregulation, and alter other biobehavioral processes relevant to health outcomes. This special issue of Psychosomatic Medicine seeks to advance our understanding of the intersection of HIV with mental health in the modern ART era. Several articles cover topics related to the prevalence and treatment of psychiatric comorbidities among PWH such as depression, suicidality, and substance use disorders. Other articles delineate biobehavioral mechanisms relevant to mental health in PWH such as inflammation, immune activation, neuroendocrine signaling, cellular aging, the microbiome-gut-brain axis, and neurobehavioral processes. Collectively, the articles in this special issue highlight the continued importance of biobehavioral and neurobehavioral mental health research in the modern ART era.
引用
收藏
页码:859 / 862
页数:4
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