Hydrogen bonding as a possible interaction for the chiral separation of DL-dopa and DL-3-O-methyl-dopa in a chiral teicoplanin column

被引：7

作者：

Wu, G ^{[1
]}

Furlanut, M ^{[1
]}

机构：

[1] Univ Udine, Fac Med & Chirurg, Cattedra Farmacol Speciale, Ist Farmacol Clin & Tossicol, I-33100 Udine, Italy

来源：

FARMACO | 1999年 / 54卷 / 03期

关键词：

dopa; 3-O-methyl-dopa; chiral separation; HPLC;

D O I：

10.1016/S0014-827X(99)00023-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The present study suggests that hydrogen bonding plays an important role in the mechanism of the chiral separation of DL-dopa and DL-3-O-methyl-dopa on a chiral teicoplanin column in high-performance liquid chromatography (HPLC). (C) 1999 Elsevier Science S.A. All rights reserved.

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收藏

页码：188 / 190

页数：3

相关论文

共 18 条

[1]

Aboul-Enein Hassan Y., 1998, Biomedical Chromatography, V12, P116, DOI 10.1002/(SICI)1099-0801(199805/06)12:3<116::AID-BMC773>3.0.CO

[2]

2-U

[3] SIMPLE AND RAPID MICROMETHOD FOR THE DETERMINATION OF LEVODOPA AND 3-O-METHYLDOPA IN HUMAN-PLASMA BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH COULOMETRIC DETECTION [J].

BARUZZI, A ;

CONTIN, M ;

ALBANI, F ;

RIVA, R .

JOURNAL OF CHROMATOGRAPHY, 1986, 375 (01) :165-169

[4] REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF THE STEREOISOMERS OF SOME SWEETENER PEPTIDES WITH A HELICAL NICKEL(II) CHELATE IN THE MOBILE-PHASE [J].

BAZYLAK, G .

JOURNAL OF CHROMATOGRAPHY A, 1994, 668 (02) :519-527

[5] SIMULTANEOUS DETERMINATION OF L-DOPA AND 3-O-METHYLDOPA IN HUMAN-SERUM BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

BEERS, MF ;

STERN, M ;

HURTIG, H ;

MELVIN, G ;

SCARPA, A .

JOURNAL OF CHROMATOGRAPHY, 1984, 336 (02) :380-384

[6] LIQUID-CHROMATOGRAPHIC DETERMINATION OF D-AMINO AND L-AMINO-ACIDS BY DERIVATIZATION WITH O-PHTHALDIALDEHYDE AND CHIRAL THIOLS [J].

BRUCKNER, H ;

HAASMANN, S ;

LANGER, M ;

WESTHAUSER, T ;

WITTNER, R ;

GODEL, H .

JOURNAL OF CHROMATOGRAPHY A, 1994, 666 (1-2) :259-273

[7] Dermatan sulfate as useful chiral selector in capillary electrophoresis [J].

Gotti, R ;

Cavrini, V ;

Andrisano, V ;

Mascellani, G .

JOURNAL OF CHROMATOGRAPHY A, 1998, 814 (1-2) :205-211

[8] Amino acid sequence and D/L-configuration determination of peptides utilizing liberated N-terminus phenylthiohydantoin amino acids [J].

Iida, T ;

Matsunaga, H ;

Santa, T ;

Fukushima, T ;

Homma, H ;

Imai, K .

JOURNAL OF CHROMATOGRAPHY A, 1998, 813 (02) :267-275

[9] SIMULTANEOUS ASSAY OF 3,4-DIHYDROXYPHENYLALANINE, CATECHOLAMINES AND O-METHYLATED METABOLITES IN HUMAN-PLASMA USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

ISHIMITSU, T ;

HIROSE, S .

JOURNAL OF CHROMATOGRAPHY, 1985, 337 (02) :239-248

[10] D-DOPA AND L-DOPA SIMILARLY ELEVATE BRAIN DOPAMINE AND PRODUCE TURNING BEHAVIOR IN RATS [J].

KAROUM, F ;

FREED, WJ ;

CHUANG, LW ;

CANNONSPOOR, E ;

WYATT, RJ ;

COSTA, E .

BRAIN RESEARCH, 1988, 440 (01) :190-194