Decatromicins A and B, new antibiotics produced by Actinomadura sp MK73-NF4 -: I.: Taxonomy, isolation, physico-chemical properties and biological activities

被引:16
作者
Momose, I [1 ]
Iinuma, H [1 ]
Kinoshita, N [1 ]
Momose, Y [1 ]
Kunimoto, S [1 ]
Hamada, M [1 ]
Takeuchi, T [1 ]
机构
[1] Inst Microbial Chem, Shinagawa Ku, Tokyo 1410021, Japan
关键词
D O I
10.7164/antibiotics.52.781
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
New antibiotics designated decatromicins A and B were isolated from the culture broth of Actinomadura sp. MK73-NF4. They were purified by butyl acetate extraction, silica gel column chromatography, silica gel TLC and Sephadex LH-20 column chromatography. Decatromicins A and B inhibited growth of Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
引用
收藏
页码:781 / 786
页数:6
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